蒙特卡罗法在调强放疗和容积旋转调强弧形治疗中的快速多叶准直器剂量计算中的应用
Monte Carlo Modeling of the Agility MLC for IMRT and VMAT Calculations.
机构信息
Department of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan
Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Osaka, Japan.
出版信息
In Vivo. 2020 Sep-Oct;34(5):2371-2380. doi: 10.21873/invivo.12050.
BACKGROUND/AIM: The Purpose of this study was to develop a Monte Carlo (MC) model for the Agility multileaf collimator (MLC) mounted and to validate its accuracy.
MATERIALS AND METHODS
To describe the Agility MLC in the BEAMnrc MC code, an existing component module code was modified to include its characteristics. The leaf characterization of the MC model was validated by comparing the calculated interleaf transmission and tongue-and-groove effect with EBT2 film and diode measurements and IMRT and VMAT calculations with film measurements.
RESULTS
Agreement between mean calculated and measured leaf transmissions was within 0.1%. The discrepancy between MC calculation and measurement in a static irregular field was less than 2%/2 mm. Gamma analysis of the comparison of MC and EBT2 film measurements in IMRT and VMAT fields yielded pass rates of 99.1% and 99.5% with 3%/3 mm criteria, respectively.
CONCLUSION
Our findings demonstrate the accuracy of the MC model using an adapted BEAMnrc component module for the Agility MLC.
背景/目的：本研究旨在开发安装在 Agility 多叶准直器（MLC）上的蒙特卡罗（MC）模型，并验证其准确性。
材料和方法
为了在 BEAMnrc MC 代码中描述 Agility MLC，修改了现有的组件模块代码以包含其特性。通过比较 EBT2 胶片和二极管测量值、IMRT 和 VMAT 计算值与胶片测量值的计算叶间透射率和榫槽效应，验证了 MC 模型的叶片特性。
结果
平均计算和测量叶片透射率之间的一致性在 0.1%以内。在静态不规则场中，MC 计算值与测量值之间的差异小于 2%/2mm。在 IMRT 和 VMAT 场中，MC 和 EBT2 胶片测量值的伽马分析分别得出 3%/3mm 标准的通过率为 99.1%和 99.5%。
结论
我们的研究结果表明，使用适用于 Agility MLC 的 BEAMnrc 组件模块的 MC 模型具有准确性。
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