Lian Qi-Xin, Zhao Wei, Li Gang, Jin Lian-Jin, Nie Hao-Jie
Department of Tumor Surgery, The First Affiliated Hospital of Jiamusi University, Jiamusi.
Department of Anatomy, Mudanjiang Medical University.
Medicine (Baltimore). 2020 Aug 14;99(33):e21585. doi: 10.1097/MD.0000000000021585.
The objective of this study is to evaluate the accuracy of radionuclide in diagnosis of bone metastasis (BM) after breast cancer surgery (BCS).
The electronic databases (Cochrane Library, MEDLINE, EMBASE, Web of Science, CBM, and CNKI) will be systematically and comprehensively searched until June 1, 2020 for eligible studies that reported the diagnosis of radionuclide in BM after BCS. In addition, we will also identify grey literatures, such as conference abstracts, and reference lists of included studies. All process of study identification, data extraction, and study methodological quality evaluation will be performed by 2 independent authors. All divergences will be settled by a third author through discussion. All data analysis will be carried out by RevMan 5.3 software (London, UK).
This study will scrutinize the most recent evidence of radionuclide in detection of BM after BCS.
This study may provide evidence of accuracy of radionuclide in diagnosis of BM following BCS.
PROSPERO CRD42020187646.
本研究的目的是评估放射性核素在乳腺癌手术（BCS）后诊断骨转移（BM）中的准确性。
将系统全面地检索电子数据库（Cochrane图书馆、MEDLINE、EMBASE、科学网、中国生物医学文献数据库和中国知网），直至2020年6月1日，以查找报告BCS后放射性核素在BM诊断中的相关合格研究。此外，我们还将识别灰色文献，如会议摘要和纳入研究的参考文献列表。研究识别、数据提取和研究方法质量评估的所有过程将由两名独立作者进行。所有分歧将由第三位作者通过讨论解决。所有数据分析将使用RevMan 5.3软件（英国伦敦）进行。
本研究将审查放射性核素在BCS后检测BM的最新证据。
本研究可能为放射性核素在BCS后诊断BM的准确性提供证据。
PROSPERO CRD42020187646。
