Badawi Abdulrahman H, Magliyah Moustafa, Allam Khalid, Alzahrani Yahya A
Vitreoretinal Division, King Khalid Eye Specialist Hospital, Riyadh, Saudi Arabia.
Department of Ophthalmology, Prince Mohammed Medical City, AlJouf, Saudi Arabia.
Middle East Afr J Ophthalmol. 2020 Jul 20;27(2):128-130. doi: 10.4103/meajo.MEAJO_177_20. eCollection 2020 Apr-Jun.
We report two cases with foveal congenital simple hamartoma of the retinal pigment epithelium (CSHRPE), as both patients presented to our retina services complaining of a unilateral decreased vision. Full ophthalmic examination and multimodal imaging were performed including fundus photography, fundus autofluorescence, optical coherence tomography, fluorescein angiography, and electrophysiological testing. Both patients presented with 20/80 vision in the affected eyes. Foveal CSHRPE was found in both eyes, along with parapapillary hyperpigmented rim, multiple pinpoint macular lesions, and few posterior pole hyperpigmented lesions. Multifocal electroretinogram showed diminished central amplitude in both eyes, with three-dimensional topography map showing blunted foveal peaks in one eye and the absence of a central peak in the other patient. Both patients had a stable vision and clinical examination of the CSHRPE during 5 and 6 years follow up, respectively. Foveal CSHRPE is usually symptomatic and results in a decline in visual acuity. Follow-up of these patients showed stable vision and clinical examination.
我们报告了两例视网膜色素上皮先天性单纯性错构瘤（CSHRPE）病例，这两位患者均因单眼视力下降前来我们的视网膜专科就诊。进行了全面的眼科检查和多模态成像，包括眼底照相、眼底自发荧光、光学相干断层扫描、荧光素血管造影和电生理检查。两位患者患眼的视力均为20/80。双眼均发现了黄斑区CSHRPE，同时伴有视乳头旁色素沉着边缘、多个黄斑区点状病变以及少数后极部色素沉着病变。多焦视网膜电图显示双眼中央振幅降低，三维地形图显示一只眼的黄斑峰变钝，另一位患者则没有中央峰。在分别为期5年和6年的随访中，两位患者的视力均保持稳定，CSHRPE的临床检查结果也稳定。黄斑区CSHRPE通常有症状，会导致视力下降。对这些患者的随访显示视力和临床检查结果稳定。
