Tao Yun-Yun, Zhou Yi, Wang Ran, Gong Xue-Qin, Zheng Jing, Yang Cui, Yang Lin, Zhang Xiao-Ming
Sichuan Key Laboratory of Medical Imaging, Department of Radiology and Medical Research Center of Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
World J Clin Cases. 2020 Aug 6;8(15):3164-3176. doi: 10.12998/wjcc.v8.i15.3164.
Traditional magnetic resonance (MR) diffusion-weighted imaging (DWI) uses a single exponential model to obtain the apparent diffusion coefficient to quantitatively reflect the diffusion motion of water molecules in living tissues, but it is affected by blood perfusion. Intravoxel incoherent motion (IVIM)-DWI utilizes a double-exponential model to obtain information on pure water molecule diffusion and microcirculatory perfusion-related diffusion, which compensates for the insufficiency of traditional DWI. In recent years, research on the application of IVIM-DWI in the diagnosis and treatment of hepatic diseases has gradually increased and has achieved considerable progress. This study mainly reviews the basic principles of IVIM-DWI and related research progress in the diagnosis and treatment of hepatic diseases.
传统的磁共振（MR）扩散加权成像（DWI）使用单指数模型来获取表观扩散系数，以定量反映水分子在活体组织中的扩散运动，但它会受到血液灌注的影响。体素内不相干运动（IVIM）-DWI利用双指数模型来获取关于纯水分子扩散和与微循环灌注相关的扩散信息，弥补了传统DWI的不足。近年来，IVIM-DWI在肝脏疾病诊断和治疗中的应用研究逐渐增多，并取得了相当大的进展。本研究主要综述IVIM-DWI的基本原理以及在肝脏疾病诊断和治疗方面的相关研究进展。
