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与 COVID-19 相关的头痛和 CSF 中的白细胞增多:病例报告。

Headache and pleocytosis in CSF associated with COVID-19: case report.

机构信息

Real Hospital Português de Beneficência de Pernambuco, Recife, Brazil.

Universidade Federal de Pernambuco, Recife, Brazil.

出版信息

Neurol Sci. 2020 Nov;41(11):3021-3022. doi: 10.1007/s10072-020-04694-x. Epub 2020 Sep 2.

Abstract

In December 2019, a new coronavirus infection was identified in China. Although the clinical presentation of COVID-19 is predominantly respiratory, more than 35%% of patients have neurological symptoms. We report an elderly female with asthenia, dry cough, anosmia, ageusia, fever, nausea, and a severe and persistent headache. She had confirmed COVID-19 using the nasal swab RT-PCR technique. Her cranial tomography was normal. The CSF analysis demonstrated a cell count of 21 cells/mm (80% lymphocytes and 20% monocytes), 34 mg/dl protein, and 79 mg/dl glucose. She improved after 4 days. Our report draws attention to the meningeal involvement of SARS-Cov-2.

摘要

2019 年 12 月,在中国发现了一种新型冠状病毒感染。虽然 COVID-19 的临床表现主要为呼吸道症状,但超过 35%的患者有神经系统症状。我们报告了一例老年女性患者,表现为乏力、干咳、嗅觉丧失、味觉丧失、发热、恶心和严重且持续的头痛。她的鼻拭子 RT-PCR 技术检测证实为 COVID-19 阳性。她的头颅 CT 正常。CSF 分析显示细胞数为 21 个/mm(80%淋巴细胞和 20%单核细胞),蛋白 34mg/dl,葡萄糖 79mg/dl。她在 4 天后好转。我们的报告引起了对 SARS-Cov-2 脑膜受累的关注。

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