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钬激光前列腺剜除术(HoLEP):良性前列腺增生症手术治疗的非尺寸依赖性金标准。

Holmium laser enucleation of the prostate (HoLEP): size-independent gold standard for surgical management of benign prostatic hyperplasia.

机构信息

Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Can J Urol. 2020 Aug;27(S3):44-50.

PMID:32876002
Abstract

INTRODUCTION

Holmium laser enucleation of the prostate (HoLEP) has become an increasingly common surgical management option for treatment of symptomatic benign prostatic hyperplasia (BPH). Transurethral resection of the prostate (TURP) has long been considered the gold standard, contemporary literature and newer guidelines indicate that HoLEP has become the new size-independent endoscopic gold standard for surgical BPH treatment.

MATERIALS AND METHODS

We provide a review and update on current HoLEP surgical techniques, outcomes, safety, and durability according to the growing body of literature.

RESULTS

The current body of literature and guidelines indicate HoLEP as a safe and effective surgical treatment for symptomatic BPH regardless of prostate size. Durable long term subjective and objective outcomes have been demonstrated in previous studies, extending beyond 10 years.

CONCLUSIONS

HoLEP continues to demonstrate durable long term efficacy for treating patients suffering from lower urinary tract symptoms (LUTS) due to BPH. The American Urological Association (AUA) guidelines recommend its use as a size-independent endoscopic treatment option. HoLEP has proven itself to be the new gold standard in surgical treatment for LUTS secondary to BPH with the ability to endoscopically treat prostates independent of size, with durable long term outcomes.

摘要

简介

钬激光前列腺剜除术(HoLEP)已成为治疗有症状的良性前列腺增生(BPH)的一种越来越常见的手术治疗选择。经尿道前列腺电切术(TURP)长期以来一直被认为是金标准,现代文献和新的指南表明,HoLEP 已成为治疗 BPH 的新的、与前列腺体积无关的内镜金标准。

材料和方法

根据不断增加的文献,我们对当前的 HoLEP 手术技术、结果、安全性和持久性进行了回顾和更新。

结果

目前的文献和指南表明,HoLEP 是一种安全有效的治疗有症状 BPH 的手术方法,无论前列腺体积大小如何。以前的研究表明,该手术具有持久的长期主观和客观疗效,超过 10 年。

结论

HoLEP 继续为因 BPH 而出现下尿路症状(LUTS)的患者提供持久的长期疗效。美国泌尿外科学会(AUA)指南推荐将其作为一种与前列腺体积无关的内镜治疗选择。HoLEP 已被证明是治疗 BPH 继发的 LUTS 的新的金标准,它具有能够根据前列腺体积大小进行内镜治疗的能力,并具有持久的长期疗效。

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Holmium laser enucleation of the prostate (HoLEP): size-independent gold standard for surgical management of benign prostatic hyperplasia.钬激光前列腺剜除术(HoLEP):良性前列腺增生症手术治疗的非尺寸依赖性金标准。
Can J Urol. 2020 Aug;27(S3):44-50.
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Eur Urol Open Sci. 2025 Aug 11;79:111-127. doi: 10.1016/j.euros.2025.07.011. eCollection 2025 Sep.
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World J Urol. 2025 Aug 18;43(1):499. doi: 10.1007/s00345-025-05871-3.
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Transurethral holmium laser enucleation of prostate shows remarkable efficacy in treating benign prostatic hyperplasia.
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Am J Transl Res. 2025 May 15;17(5):3665-3673. doi: 10.62347/RKJN6285. eCollection 2025.
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Magnetic resonance imaging-guided transurethral ultrasound ablation for benign prostatic obstruction: 1-year clinical outcomes of a phase II study.磁共振成像引导经尿道超声消融治疗良性前列腺梗阻:一项II期研究的1年临床结果
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Prospective analysis of the morcellation efficiency of a novel device (MultiCut®) for prostate laser enucleation.新型设备(MultiCut®)用于前列腺激光剜除术的粉碎效率的前瞻性分析。
Int Urol Nephrol. 2025 May 9. doi: 10.1007/s11255-025-04568-1.
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