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[复发性多软骨炎:多样化的疾病表现]

[Relapsing polychondritis: a diversified disease picture].

作者信息

Schlapbach P, Im Hof V

机构信息

Rheumatologische Universitätsklinik und Poliklinik, Inselspital, Bern.

出版信息

Schweiz Med Wochenschr. 1988 Apr 16;118(15):535-40.

PMID:3287607
Abstract

Relapsing polychondritis is a rare, at times fatal systemic disease involving inflammatory destruction mainly of cartilaginous structures. The sensory organs, respiratory tract, cardiovascular system and kidneys are most frequently involved. Based on the current state of knowledge it seems probable that relapsing polychondritis is an autoimmune disease. Early involvement of the respiratory tract and kidneys, anemia, arthritis and saddle-nose deformity are associated with poor prognosis. 2 cases of relapsing polychondritis (one with erosive symmetrical polyarthritis and the second with massive involvement of the respiratory tract) are presented.

摘要

复发性多软骨炎是一种罕见的、有时会致命的全身性疾病,主要累及软骨结构的炎性破坏。感觉器官、呼吸道、心血管系统和肾脏最常受累。根据目前的知识状况,复发性多软骨炎似乎很可能是一种自身免疫性疾病。呼吸道和肾脏的早期受累、贫血、关节炎和鞍鼻畸形与预后不良有关。本文报告2例复发性多软骨炎(1例为侵蚀性对称性多关节炎,另1例为呼吸道广泛受累)。

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