Dumurgier Julien, Sabia Séverine
Centre de neurologie cognitive, hôpital Lariboisière-Fernand- Widal, Assistance publique-Hôpitaux de Paris, université de Paris, Paris, France.
Inserm U1153, équipe Épidémiologie du vieillissement et des maladies neurodégénératives, université de Paris, Paris, France.
Rev Prat. 2020 Feb;70(2):149-151.
Epidemiology of Alzheimer's disease: latest trends. Alzheimer's disease (AD) is the main cause of dementia in the elderly population, and the 5th leading cause of mortality. It afflicts around 44 million people worldwide. France is currently counting 1.1 million people suffering from AD, with the occurrence of 225.000 new patients each year. Due to the rapid aging of the population, the number of patients should almost double by 2050. Recent epidemiological studies found a decrease in the incidence of AD, which could be partly explained by a better care of some risk factors associated with the disease. The recent development of non-invasive biomarkers of AD allows to a better understanding of the pre-clinical phase of the disease in population.
最新趋势。阿尔茨海默病（AD）是老年人群痴呆症的主要病因，也是第五大死因。全球约有4400万人受其折磨。法国目前有110万人患有AD，每年新增22.5万患者。由于人口快速老龄化，到2050年患者数量预计将几乎翻倍。最近的流行病学研究发现AD发病率有所下降，这可能部分归因于对一些与该疾病相关风险因素的更好管控。AD非侵入性生物标志物的最新进展有助于更好地了解该疾病在人群中的临床前期阶段。
