Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan; Toyota Municipal Child Development Center, Toyota, Japan.
Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Brain Dev. 2021 Feb;43(2):181-185. doi: 10.1016/j.braindev.2020.08.007. Epub 2020 Aug 30.
Bottom shuffling is a locomotion strategy that precedes independent walking in some infants. Shuffling babies are generally considered to have favorable outcomes. The aim of the present study was to reveal clinical features and neurodevelopmental outcomes of shuffling babies who visited a child developmental center.
We studied 48 shuffling babies who visited Toyota Municipal Child Development Center from April 2007 to March 2015. We excluded patients with cerebral palsy, Down syndrome, or congenital disorders. In 2018, we retrospectively reviewed the clinical charts of the enrolled children. We investigated family history, neurological findings, and the developmental outcome during the follow-up period.
During the follow-up period, 20 children (42%) were diagnosed with ASD. Gross motor development in infancy was not different between infants with and without ASD. The rate of poor eye contact at the first visit and a delay in the first word speech were significantly higher in infants with ASD than in infants without ASD. A family history of bottom shuffling was significantly less frequent in infants with ASD (10%) than in those without (39%).
Some of bottom shufflers may represent ASD during follow-up. Paying attention to social and cognitive functions in shuffling babies is important.
在一些婴儿中，底部摇晃是一种先于独立行走的运动策略。通常认为摇晃婴儿的预后较好。本研究旨在揭示到儿童发育中心就诊的摇晃婴儿的临床特征和神经发育结局。
我们研究了 2007 年 4 月至 2015 年 3 月期间到丰田市儿童发育中心就诊的 48 名摇晃婴儿。我们排除了脑瘫、唐氏综合征或先天性疾病的患者。2018 年，我们回顾性地查阅了入组儿童的临床记录。我们调查了家族史、神经学表现以及随访期间的发育结果。
在随访期间，有 20 名儿童（42%）被诊断为自闭症谱系障碍。婴幼儿粗大运动发育在自闭症谱系障碍患儿和非自闭症谱系障碍患儿之间没有差异。在有自闭症谱系障碍的婴儿中，首次就诊时眼神接触不良和首次言语延迟的发生率明显高于无自闭症谱系障碍的婴儿。有自闭症谱系障碍的婴儿的家族底部摇晃史明显少于无自闭症谱系障碍的婴儿（10%比 39%）。
在随访中，一些底部摇晃者可能代表自闭症谱系障碍。关注摇晃婴儿的社交和认知功能很重要。
