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Single-cell transcriptional profile of ACE2 in healthy and failing human hearts.

作者信息

Zhou Yitian, Huang Yongfa, Song Xiaomin, Guo Xiaoxiao, Pang Junling, Wang Jing, Zhang Shuyang, Wang Chen

机构信息

State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Department of Pathophysiology, Peking Union Medical College, Beijing, 100730, China.

Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China.

出版信息

Sci China Life Sci. 2021 Apr;64(4):652-655. doi: 10.1007/s11427-020-1787-5. Epub 2020 Sep 1.

DOI:10.1007/s11427-020-1787-5
PMID:32880862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7471532/
Abstract
摘要

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Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence.高血压、血栓形成、肾衰竭与糖尿病：新型冠状病毒肺炎是一种内皮疾病吗？临床及基础证据的综合评估
J Clin Med. 2020 May 11;9(5):1417. doi: 10.3390/jcm9051417.
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Severe COVID-19 infection associated with endothelial activation.严重的2019冠状病毒病感染与内皮细胞激活有关。
Thromb Res. 2020 Jun;190:62. doi: 10.1016/j.thromres.2020.04.014. Epub 2020 Apr 15.
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Incidence of thrombotic complications in critically ill ICU patients with COVID-19.COVID-19 重症监护病房危重症患者的血栓并发症发生率。
Thromb Res. 2020 Jul;191:145-147. doi: 10.1016/j.thromres.2020.04.013. Epub 2020 Apr 10.
4
The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2.人类心脏中的 ACE2 表达表明了 SARS-CoV-2 感染患者心脏损伤的新潜在机制。
Cardiovasc Res. 2020 May 1;116(6):1097-1100. doi: 10.1093/cvr/cvaa078.
5
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.中国武汉严重 COVID-19 患者的临床病程和结局：一项单中心、回顾性、观察性研究。
Lancet Respir Med. 2020 May;8(5):475-481. doi: 10.1016/S2213-2600(20)30079-5. Epub 2020 Feb 24.
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