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一项针对接受抗逆转录病毒治疗的艾滋病毒感染者中饮酒男性的多层次干预措施,以减少污名化:来自印度的一项随机对照试验的结果。

A multilevel intervention to reduce stigma among alcohol consuming men living with HIV receiving antiretroviral therapy: findings from a randomized control trial in India.

机构信息

Population Council, New Delhi, India.

Institute for Community Research, Hartford.

出版信息

AIDS. 2020 Sep 1;34 Suppl 1:S83-S92. doi: 10.1097/QAD.0000000000002604.

Abstract

OBJECTIVE

To examine the effectiveness of a multilevel intervention to reduce HIV stigma among alcohol consuming men living with HIV in India.

DESIGN

A crossover randomized controlled trial in four sites.

SETTING

Government ART centres (ARTCs) offering core services in the greater Mumbai area.

PARTICIPANTS

Seven hundred and fifty two (188 per site) alcohol-consuming male PLHIV on ART were recruited.

INTERVENTION

Multilevel intervention to reduce alcohol consumption and promote adherence by addressing stigma, implemented at the individual (individual counselling, IC), group (group intervention, GI) and community levels (collective advocacy, CA) in three distinct sequences over three cycles of 9 months each.

MAIN OUTCOME MEASURE

HIV stigma, measured using the 16-item Berger Stigma scale.

METHODS

The article examines the effectiveness of the interventions to reduce stigma using Linear Mixed Model regression.

RESULTS

At baseline, 57% of participants had moderate-high levels of stigma (scores >40). All three counseling interventions were effective in reducing stigma when delivered individually, in the first cycle (collective advocacy: βcoeff = -9.71; p < 0.001; group intervention: βcoeff = -5.22; p < 0.001; individual counselling: βcoeff = -4.43; p < 0.001). At then end of the second cycle, effects from the first cycle were sustained with no significant change in stigma scores. At the end of the third cycle, the site, which received CA+IC+GI sequence had maximum reduction in stigma scores (βcoeff = -10.29; p < 0.001), followed by GI+CA+IC (βcoeff = -8.23, p < 0.001).

CONCLUSION

Baseline findings suggest that stigma remains a problem even with experienced patients, despite advances in treatment and adherence. Results of multilevel stigma reduction interventions argue for inclusion in HIV prevention and treatment program.

摘要

目的

考察一项针对印度饮酒 HIV 感染者的多层次干预措施减少 HIV 污名的效果。

设计

在四个地点进行的交叉随机对照试验。

地点

在孟买大都市区提供核心服务的政府艾滋病治疗中心 (ARTC)。

参与者

招募了 752 名(每个地点 188 名)接受抗逆转录病毒治疗的饮酒男性 PLHIV。

干预措施

多层次干预措施,通过解决污名问题,减少酒精消费和促进依从性,在个体(个体咨询,IC)、群体(群体干预,GI)和社区层面(集体倡导,CA)三个不同的序列中实施,每个周期为 9 个月,共三个周期。

主要结局测量

使用 16 项 Berger 耻辱量表测量 HIV 耻辱感。

方法

本文使用线性混合模型回归检验干预措施减少耻辱感的效果。

结果

在基线时,57%的参与者具有中度高的耻辱感水平(得分>40)。当个体实施时,所有三种咨询干预措施在第一周期都有效降低了耻辱感(集体倡导:β系数= -9.71;p <0.001;群体干预:β系数= -5.22;p <0.001;个体咨询:β系数= -4.43;p <0.001)。在第二周期结束时,第一周期的效果得到了维持,耻辱感评分没有显著变化。在第三周期结束时,接受 CA+IC+GI 序列的站点的耻辱感评分降低最多(β系数= -10.29;p <0.001),其次是 GI+CA+IC(β系数= -8.23,p <0.001)。

结论

基线结果表明,尽管治疗和依从性取得了进展,但即使是经验丰富的患者,耻辱感仍然是一个问题。减少多层次耻辱感的干预措施的结果表明,应该将其纳入艾滋病毒预防和治疗计划。

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