• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项针对接受抗逆转录病毒治疗的艾滋病毒感染者中饮酒男性的多层次干预措施,以减少污名化:来自印度的一项随机对照试验的结果。

A multilevel intervention to reduce stigma among alcohol consuming men living with HIV receiving antiretroviral therapy: findings from a randomized control trial in India.

机构信息

Population Council, New Delhi, India.

Institute for Community Research, Hartford.

出版信息

AIDS. 2020 Sep 1;34 Suppl 1:S83-S92. doi: 10.1097/QAD.0000000000002604.

DOI:10.1097/QAD.0000000000002604
PMID:32881797
Abstract

OBJECTIVE

To examine the effectiveness of a multilevel intervention to reduce HIV stigma among alcohol consuming men living with HIV in India.

DESIGN

A crossover randomized controlled trial in four sites.

SETTING

Government ART centres (ARTCs) offering core services in the greater Mumbai area.

PARTICIPANTS

Seven hundred and fifty two (188 per site) alcohol-consuming male PLHIV on ART were recruited.

INTERVENTION

Multilevel intervention to reduce alcohol consumption and promote adherence by addressing stigma, implemented at the individual (individual counselling, IC), group (group intervention, GI) and community levels (collective advocacy, CA) in three distinct sequences over three cycles of 9 months each.

MAIN OUTCOME MEASURE

HIV stigma, measured using the 16-item Berger Stigma scale.

METHODS

The article examines the effectiveness of the interventions to reduce stigma using Linear Mixed Model regression.

RESULTS

At baseline, 57% of participants had moderate-high levels of stigma (scores >40). All three counseling interventions were effective in reducing stigma when delivered individually, in the first cycle (collective advocacy: βcoeff = -9.71; p < 0.001; group intervention: βcoeff = -5.22; p < 0.001; individual counselling: βcoeff = -4.43; p < 0.001). At then end of the second cycle, effects from the first cycle were sustained with no significant change in stigma scores. At the end of the third cycle, the site, which received CA+IC+GI sequence had maximum reduction in stigma scores (βcoeff = -10.29; p < 0.001), followed by GI+CA+IC (βcoeff = -8.23, p < 0.001).

CONCLUSION

Baseline findings suggest that stigma remains a problem even with experienced patients, despite advances in treatment and adherence. Results of multilevel stigma reduction interventions argue for inclusion in HIV prevention and treatment program.

摘要

目的

考察一项针对印度饮酒 HIV 感染者的多层次干预措施减少 HIV 污名的效果。

设计

在四个地点进行的交叉随机对照试验。

地点

在孟买大都市区提供核心服务的政府艾滋病治疗中心 (ARTC)。

参与者

招募了 752 名(每个地点 188 名)接受抗逆转录病毒治疗的饮酒男性 PLHIV。

干预措施

多层次干预措施,通过解决污名问题,减少酒精消费和促进依从性,在个体(个体咨询,IC)、群体(群体干预,GI)和社区层面(集体倡导,CA)三个不同的序列中实施,每个周期为 9 个月,共三个周期。

主要结局测量

使用 16 项 Berger 耻辱量表测量 HIV 耻辱感。

方法

本文使用线性混合模型回归检验干预措施减少耻辱感的效果。

结果

在基线时,57%的参与者具有中度高的耻辱感水平(得分>40)。当个体实施时,所有三种咨询干预措施在第一周期都有效降低了耻辱感(集体倡导:β系数= -9.71;p <0.001;群体干预:β系数= -5.22;p <0.001;个体咨询:β系数= -4.43;p <0.001)。在第二周期结束时,第一周期的效果得到了维持,耻辱感评分没有显著变化。在第三周期结束时,接受 CA+IC+GI 序列的站点的耻辱感评分降低最多(β系数= -10.29;p <0.001),其次是 GI+CA+IC(β系数= -8.23,p <0.001)。

结论

基线结果表明,尽管治疗和依从性取得了进展,但即使是经验丰富的患者,耻辱感仍然是一个问题。减少多层次耻辱感的干预措施的结果表明,应该将其纳入艾滋病毒预防和治疗计划。

相似文献

1
A multilevel intervention to reduce stigma among alcohol consuming men living with HIV receiving antiretroviral therapy: findings from a randomized control trial in India.一项针对接受抗逆转录病毒治疗的艾滋病毒感染者中饮酒男性的多层次干预措施,以减少污名化:来自印度的一项随机对照试验的结果。
AIDS. 2020 Sep 1;34 Suppl 1:S83-S92. doi: 10.1097/QAD.0000000000002604.
2
Multilevel and Multifactorial Interventions to Reduce Alcohol Consumption and Improve ART Adherence and Related Factors Among HIV Positive Men in Mumbai, India.多层面多因素干预措施减少印度孟买 HIV 阳性男性的饮酒量并改善 ART 依从性及相关因素
AIDS Behav. 2021 Dec;25(Suppl 3):290-301. doi: 10.1007/s10461-021-03303-y. Epub 2021 May 20.
3
Depression Among Alcohol Consuming, HIV Positive Men on ART Treatment in India.印度接受抗逆转录病毒治疗的酒精消费艾滋病毒阳性男性中的抑郁情况。
AIDS Behav. 2019 Jun;23(6):1623-1633. doi: 10.1007/s10461-018-2339-3.
4
Assessing the Effectiveness of Multilevel Intervention Sequences on "Tension" Among Men Living with HIV: A Randomized-Control Trial.评估多级干预序列对艾滋病毒感染者男性“紧张感”的有效性:一项随机对照试验。
Int J Behav Med. 2024 Jul 29. doi: 10.1007/s12529-024-10310-5.
5
The Role of Alcohol on Antiretroviral Therapy Adherence Among Persons Living With HIV in Urban India.酒精对印度城市地区艾滋病毒感染者抗逆转录病毒治疗依从性的影响
J Stud Alcohol Drugs. 2017 Sep;78(5):716-724. doi: 10.15288/jsad.2017.78.716.
6
A cluster randomised controlled trial protocol of an adapted intervention for alcohol use disorders in people living with HIV and AIDS: impact on alcohol use, general functional ability, quality of life and adherence to HAART.一项针对艾滋病毒/艾滋病感染者酒精使用障碍的适应性干预措施的整群随机对照试验方案:对酒精使用、总体功能能力、生活质量及高效抗逆转录病毒治疗依从性的影响
BMC Psychiatry. 2017 Jan 28;17(1):44. doi: 10.1186/s12888-017-1208-3.
7
Changes in Internalized Stigma and HIV Health Outcomes in Individuals New to HIV Care: The Mediating Roles of Depression and Treatment Self-Efficacy.HIV 新感染者的内化污名与 HIV 健康结局的变化:抑郁和治疗自我效能的中介作用。
AIDS Patient Care STDS. 2020 Nov;34(11):491-497. doi: 10.1089/apc.2020.0114.
8
Treatment adherence in HIV stigmatized environments in South Africa: stigma avoidance and medication management.南非艾滋病污名化环境下的治疗依从性:污名规避与药物管理
Int J STD AIDS. 2019 Mar;30(4):362-370. doi: 10.1177/0956462418813047. Epub 2018 Nov 30.
9
Internalized HIV stigma predicts subsequent viremia in US HIV patients through depressive symptoms and antiretroviral therapy adherence.内在 HIV 污名通过抑郁症状和抗逆转录病毒治疗依从性预测美国 HIV 患者随后的病毒血症。
AIDS. 2020 Sep 1;34(11):1665-1671. doi: 10.1097/QAD.0000000000002595.
10
Identifying the Intersection of Alcohol, Adherence and Sex in HIV Positive Men on ART Treatment in India Using an Adapted Timeline Followback Procedure.采用适应性时间线追溯程序确定印度接受抗逆转录病毒治疗的HIV阳性男性中酒精、依从性和性别的交叉点。
AIDS Behav. 2017 Nov;21(Suppl 2):228-242. doi: 10.1007/s10461-017-1916-1.

引用本文的文献

1
A Rapid Review of HIV-Related Stigma-Reduction Randomized Controlled Trials.一项关于减少与艾滋病毒相关耻辱感的随机对照试验的快速综述。
AIDS Behav. 2025 Apr 5. doi: 10.1007/s10461-025-04673-3.
2
Assessing the Effectiveness of Multilevel Intervention Sequences on "Tension" Among Men Living with HIV: A Randomized-Control Trial.评估多级干预序列对艾滋病毒感染者男性“紧张感”的有效性:一项随机对照试验。
Int J Behav Med. 2024 Jul 29. doi: 10.1007/s12529-024-10310-5.
3
Longitudinal trajectories of depressive symptoms among alcohol consuming men with HIV in India.
印度 HIV 阳性饮酒男性的抑郁症状纵向轨迹。
J Affect Disord. 2024 Jan 1;344:674-681. doi: 10.1016/j.jad.2023.10.057. Epub 2023 Oct 11.
4
Alcohol Use, HIV Stigma and Quality of Life Among Alcohol Consuming Men Living with HIV in India: A Mediation Analysis.印度饮酒 HIV 感染者中的饮酒行为、HIV 污名与生活质量:中介分析
AIDS Behav. 2023 Oct;27(10):3272-3284. doi: 10.1007/s10461-023-04047-7. Epub 2023 Apr 8.
5
Gender minority stress and access to health care services among transgender women and transfeminine people: results from a cross-sectional study in China.跨性别女性和跨性别男性中的性别少数群体压力与获得医疗保健服务:来自中国一项横断面研究的结果。
BMC Infect Dis. 2021 Oct 14;21(1):1065. doi: 10.1186/s12879-021-06782-5.