Department of Public Health Sciences, University of Connecticut School of Medicine, 263 Farmington Ave, Farmington, CT, 06030, USA.
Department of Infectious Diseases, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
AIDS Behav. 2021 Dec;25(Suppl 3):290-301. doi: 10.1007/s10461-021-03303-y. Epub 2021 May 20.
Alcohol use has a deleterious effect on the health status of persons living with HIV, negatively affecting antiretroviral adherence and increasing the risk of transmission. Alcohol use is not an isolated behavior but intimately linked to stigma and poor psychological status among other factors. This paper utilizes a crossover design to test the efficacy of three multilevel interventions, individual counselling (IC), group intervention (GI) and collective advocacy (CA) for change, among HIV positive males who consume alcohol, treated at five ART Centers in urban Maharashtra, India. While GI shows a significant effect on the largest number of outcome variables, IC through its psychosocial emphasis demonstrated a significant impact over time on stigma and depression, and CA with its emphasis on societal change showed positive impact on stigma and advocacy for self and others. Each of the interventions had variable effects on CD4 count and viral load.Clinical Registration Number: NCT03746457; Clinical Trial.Gov.
饮酒会对 HIV 感染者的健康状况产生有害影响，降低抗逆转录病毒药物的依从性，并增加传播风险。饮酒不是一种孤立的行为，而是与耻辱感和较差的心理状态等其他因素密切相关。本文采用交叉设计，在印度马哈拉施特拉邦五个城市的五个艾滋病治疗中心，对饮酒的 HIV 阳性男性进行了三种多层次干预措施（个体咨询、团体干预和集体倡导）的效果测试。虽然团体干预在最大数量的结果变量上显示出显著效果，但个体咨询通过其社会心理重点，随着时间的推移，对耻辱感和抑郁产生了显著影响，而集体倡导通过其对社会变革的强调，对耻辱感和为自己和他人倡导产生了积极影响。每种干预措施对 CD4 计数和病毒载量的影响都不同。临床试验注册号：NCT03746457；ClinicalTrials.gov。
