Weisenthal R, Frayer W C, Nichols C W, Eagle R C
Department of Ophthalmology, University of Pennsylvania, Philadelphia.
Br J Ophthalmol. 1988 Apr;72(4):248-52. doi: 10.1136/bjo.72.4.248.
Malignant lymphocytic lymphoma rarely involves the eye. In two patients we found ocular signs and symptoms as the initial presentation of systemic disease. In the first patient periorbital swelling and ptosis of one year's duration ultimately proved to be the result of malignant lymphoma. After resolution of swelling and ptosis with chemotherapy, the patient returned with diffuse iris involvement and uveitis with a hypopyon. In the second patient an acute change of refractive error proved to be the result of a lymphomatous deposit in the choroid. In both instances common symptoms were the initial manifestations of a diffuse malignant disease.
恶性淋巴细胞淋巴瘤很少累及眼部。我们发现有两名患者以眼部体征和症状作为全身性疾病的首发表现。首例患者持续一年的眶周肿胀和上睑下垂最终被证实是恶性淋巴瘤所致。化疗后肿胀和上睑下垂消退,但患者又出现了弥漫性虹膜受累及伴有前房积脓的葡萄膜炎。第二例患者屈光不正的急性改变被证实是脉络膜淋巴瘤沉积所致。在这两例中,常见症状均为弥漫性恶性疾病的初始表现。