Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Expert Rev Respir Med. 2011 Jun;5(3):353-61. doi: 10.1586/ers.11.19.
Bronchiolitis obliterans organizing pneumonia is an inflammatory lung disease involving the distal bronchioles, respiratory bronchioles, bronchiolar ducts and alveoli. Its cause is generally unknown, but there are several known causes and associated systemic diseases. The clinical features include cough, shortness of breath and bilateral crackles. The vital capacity is slightly decreased, and the diffusing capacity is moderately to severely decreased. The high-resolution chest CT scan shows bilateral ground-glass opacities with air bronchograms and triangular, pleura-based opacities. Corticosteroid therapy is the best treatment option. The outcome of patients suffering from bronchiolitis obliterans organizing pneumonia is good, as up to 80% of individuals will be cured.
闭塞性细支气管炎伴机化性肺炎是一种累及细支气管、呼吸性细支气管、细支气管导管和肺泡的炎症性肺部疾病。其病因通常未知，但有几种已知的病因和相关的系统性疾病。其临床特征包括咳嗽、呼吸急促和双肺爆裂音。肺活量略有下降，弥散量中度至重度下降。高分辨率胸部 CT 扫描显示双侧磨玻璃影伴空气支气管征和三角形、胸膜基的混浊。皮质类固醇治疗是最佳治疗选择。闭塞性细支气管炎伴机化性肺炎患者的预后良好，多达 80%的患者可被治愈。
