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角膜穿孔伴虹膜植入角膜后的自愈

Corneal Perforation Self-Healing with an Iris Plug in the Cornea.

作者信息

Muceniece Liene, Markevica Inesa, Laganovska Guna

机构信息

Ophthalmology Department, Pauls Stradins Clinical University Hospital, Riga, Latvia.

Department of Ophthalmology, Riga Stradins University, Riga, Latvia.

出版信息

Case Rep Ophthalmol. 2020 Jul 13;11(2):330-335. doi: 10.1159/000508816. eCollection 2020 May-Aug.

DOI:10.1159/000508816
PMID:32884546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7443679/
Abstract

Keratitis treatment outcome is usually dependent on the targeted treatment of the cause. We want to present a small corneal ulcer of unidentified origin that progressed into corneal melting and resulted in corneal perforation. The patient had a widespread antibacterial and fungal treatment and an ophthalmological follow-up with slit-lamp examination and AS-OCT. The spontaneous iris plug in the cornea helped to solve the anterior chamber collapse and made permanent anatomical changes in the anterior part. A 45-week follow-up found a hyperdense stromal corneal scar with 556-µm-wide stable iris-cornea contact and BCVA of 0.8. As a result, an iris plug in the cornea after corneal perforation can have a positive effect on healing and lead to good visual outcome.

摘要

角膜炎的治疗结果通常取决于针对病因的治疗。我们想呈现一例病因不明的小角膜溃疡,其进展为角膜溶解并导致角膜穿孔。该患者接受了广泛的抗菌和抗真菌治疗,并通过裂隙灯检查和AS-OCT进行眼科随访。角膜内自发形成的虹膜堵塞有助于解决前房塌陷问题,并使前部发生永久性解剖学改变。45周的随访发现角膜基质有高密度瘢痕,虹膜与角膜接触稳定,宽度为556微米,最佳矫正视力为0.8。因此,角膜穿孔后角膜内的虹膜堵塞对愈合可能有积极影响,并能带来良好的视觉效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/a983df632359/cop-0011-0330-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/e29ed62e1ff3/cop-0011-0330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/00c92c5b1d74/cop-0011-0330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/a983df632359/cop-0011-0330-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/e29ed62e1ff3/cop-0011-0330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/00c92c5b1d74/cop-0011-0330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598d/7443679/a983df632359/cop-0011-0330-g03.jpg

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本文引用的文献

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Bacterial Keratitis: Isolated Organisms and Antibiotic Resistance Patterns in San Francisco.细菌性角膜炎:旧金山的分离菌株及抗生素耐药模式
Cornea. 2018 Jan;37(1):84-87. doi: 10.1097/ICO.0000000000001417.
2
Infectious corneal ulcers.感染性角膜溃疡
Dis Mon. 2017 Feb;63(2):33-37. doi: 10.1016/j.disamonth.2016.09.003. Epub 2016 Dec 22.
3
Non-traumatic corneal perforations: aetiology, treatment and outcomes.非创伤性角膜穿孔:病因、治疗及预后
Br J Ophthalmol. 2017 May;101(5):634-639. doi: 10.1136/bjophthalmol-2016-308618. Epub 2016 Aug 8.
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Topical corticosteroids as adjunctive therapy for bacterial keratitis.局部用皮质类固醇作为细菌性角膜炎的辅助治疗
Cochrane Database Syst Rev. 2014 Oct 16;10(10):CD005430. doi: 10.1002/14651858.CD005430.pub3.
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Management of a small paracentral corneal perforation using iatrogenic iris incarceration and tissue adhesive.使用医源性虹膜嵌顿和组织粘合剂治疗小的角膜旁中央穿孔
Case Rep Ophthalmol. 2012 May;3(2):226-9. doi: 10.1159/000341094. Epub 2012 Jul 10.
6
Characteristic clinical features as an aid to the diagnosis of suppurative keratitis caused by filamentous fungi.有助于诊断丝状真菌引起的化脓性角膜炎的特征性临床特征。
Br J Ophthalmol. 2005 Dec;89(12):1554-8. doi: 10.1136/bjo.2005.076315.