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一例以咯血为表现的原发性纵隔内胚窦瘤罕见病例。

A Rare Case of Primary Mediastinal Endodermal Sinus Tumor Presenting with Hemoptysis.

作者信息

Noor Muhammad, Leal Berenice L, Patel Dhruv

机构信息

Radiology, AdventHealth Orlando, Orlando, USA.

Radiology, Osceola Regional Medical Center, Kissimmee, USA.

出版信息

Cureus. 2020 Aug 2;12(8):e9517. doi: 10.7759/cureus.9517.

DOI:10.7759/cureus.9517
PMID:32884873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7462652/
Abstract

Mediastinal non-seminomatous germ cell tumors (NSGCTs) are very rare, with an approximate annual incidence of 500 in the United States. Here, we present a case of a 22-year-old male presenting with hemoptysis who was found to have primary mediastinal NSGCT, endodermal sinus tumor type (or yolk sac type). We review the imaging findings, pathology, and treatment of primary mediastinal endodermal sinus tumors.

摘要

纵隔非精原细胞性生殖细胞肿瘤（NSGCTs）非常罕见，在美国每年的发病率约为500例。在此，我们报告一例22岁男性患者，因咯血就诊，被发现患有原发性纵隔NSGCT，内胚窦瘤型（或卵黄囊型）。我们回顾原发性纵隔内胚窦瘤的影像学表现、病理学及治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/91b51e5dab35/cureus-0012-00000009517-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/520018d74272/cureus-0012-00000009517-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/5ac1ae846b0c/cureus-0012-00000009517-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/91b51e5dab35/cureus-0012-00000009517-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/520018d74272/cureus-0012-00000009517-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/5ac1ae846b0c/cureus-0012-00000009517-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ad/7462652/91b51e5dab35/cureus-0012-00000009517-i03.jpg

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本文引用的文献

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J Thorac Cardiovasc Surg. 2021 Jun;161(6):1947-1959.e1. doi: 10.1016/j.jtcvs.2020.01.118. Epub 2020 Apr 22.
2
Primary mediastinal yolk sac tumor treated with platinum-based chemotherapy and extended resection: Report of seven cases.采用铂类为基础的化疗联合扩大切除术治疗原发性纵隔卵黄囊瘤 7 例报告
Thorac Cancer. 2018 Apr;9(4):491-494. doi: 10.1111/1759-7714.12591. Epub 2018 Jan 10.
3
A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male.
一名老年男性原发性前纵隔卵黄囊瘤的罕见病例。
Case Rep Oncol Med. 2016;2016:8961486. doi: 10.1155/2016/8961486. Epub 2016 Apr 6.
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5
A 25-year single institution experience with surgery for primary mediastinal nonseminomatous germ cell tumors.一家机构25年原发性纵隔非精原细胞瘤生殖细胞肿瘤手术治疗经验。
Ann Thorac Surg. 2008 Feb;85(2):371-8. doi: 10.1016/j.athoracsur.2007.09.020.
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Extragonadal germ cell tumors: a review with emphasis on pathologic features, clinical prognostic variables, and differential diagnostic considerations.性腺外生殖细胞肿瘤：一篇重点论述病理特征、临床预后变量及鉴别诊断考量因素的综述
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