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维持性血液透析的慢性肾脏病患者失眠的相关性

Association of Insomnia in Patients with Chronic Kidney Disease on Maintenance Hemodialysis.

作者信息

Rehman Omer Farooq, Rauf Uzma, Rauf Maryam, Aziz Sana, Faraz Ahmad, Jameel Farah Anum

机构信息

Urology, Armed Forces Institute of Urology, Rawalpindi, PAK.

Nephrology, Khyber Teaching Hospital, Peshawar, PAK.

出版信息

Cureus. 2020 Aug 2;12(8):e9520. doi: 10.7759/cureus.9520.

Abstract

Objective To determine the frequency of insomnia in patients with chronic kidney disease (CKD) on maintenance hemodialysis (HD) Study design Cross-sectional (descriptive) Study duration From July 20, 2019, to January 20, 2020 Study settings Department of Nephrology, Khyber Teaching Hospital, Peshawar Materials and methods A total of 148 patients diagnosed with CKD and on maintenance HD were selected for the study in a consecutive sampling manner and checked for insomnia. Results Out of 148 patients included in the study, there were 64.9% male and 35.1% female patients. The mean duration of CKD (months) was 13.9 ± 6.3. The mean number of sessions for hemodialysis done in all patients was 16.8 ± 5.3. On careful interviewing of the patient, difficulty in falling asleep was recorded in 28.4%, difficulty in staying asleep in 41.9%, problems in waking up early in 34.5%, and insomnia interfering in routine life activities in 28.4%. Overall, insomnia was recorded in 36.5% of patients and was found to have a significant correlation with the number of dialysis sessions (p-value 0.000). Conclusion Insomnia is a frequent disorder associated with CKD patients on maintenance HD. There are very few studies establishing its pathogenesis and risk factors. We recommend further multicenter studies to detect the course of insomnia in association with CKD on HD and its potential impact on the overall quality of life of patients with CKD.

摘要

目的 确定维持性血液透析(HD)的慢性肾脏病(CKD)患者中失眠的发生率 研究设计 横断面(描述性)研究 研究持续时间 2019年7月20日至2020年1月20日 研究地点 白沙瓦开伯尔教学医院肾脏病科 材料与方法 采用连续抽样的方式选取148例确诊为CKD并接受维持性HD的患者进行研究,并检查是否存在失眠。 结果 纳入研究的148例患者中,男性占64.9%,女性占35.1%。CKD的平均病程(月)为13.9±6.3。所有患者进行血液透析的平均次数为16.8±5.3。在对患者进行仔细询问时,记录到入睡困难的患者占28.4%,睡眠维持困难的患者占41.9%,早醒问题的患者占34.5%,失眠干扰日常生活活动的患者占28.4%。总体而言,36.5%的患者存在失眠,且发现其与透析次数有显著相关性(p值0.000)。 结论 失眠是维持性HD的CKD患者中常见的一种疾病。很少有研究阐明其发病机制和危险因素。我们建议开展进一步的多中心研究,以检测与HD的CKD相关的失眠病程及其对CKD患者总体生活质量的潜在影响。

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本文引用的文献

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Exploring sleep disorders in patients with chronic kidney disease.探索慢性肾脏病患者的睡眠障碍
Nat Sci Sleep. 2018 Jan 31;10:35-43. doi: 10.2147/NSS.S125839. eCollection 2018.
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Sleep disorders and chronic kidney disease.睡眠障碍与慢性肾脏病
World J Nephrol. 2016 May 6;5(3):224-32. doi: 10.5527/wjn.v5.i3.224.

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