氟烯和烯丙基异丙基乙酰胺在体内对不同形式细胞色素P - 450的降解作用。 - Suppr | 超能文献

The degradation of different forms of cytochrome P-450 in vivo by fluroxene and allyl-iso-propylacetamide.

作者信息

Bradshaw J J, Ziman M R, Ivanetich K M

出版信息

Biochem Biophys Res Commun. 1978 Dec 14;85(3):859-66. doi: 10.1016/0006-291x(78)90623-x.

DOI:10.1016/0006-291x(78)90623-x

PMID:32885

Abstract

摘要

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1

The degradation of different forms of cytochrome P-450 in vivo by fluroxene and allyl-iso-propylacetamide.氟烯和烯丙基异丙基乙酰胺在体内对不同形式细胞色素P - 450的降解作用。

Biochem Biophys Res Commun. 1978 Dec 14;85(3):859-66. doi: 10.1016/0006-291x(78)90623-x.

2

Reaction schemes for the degradation of cytochrome P-450 by allyl-iso-propylacetamide and fluroxene.烯丙基异丙基乙酰胺和氟烷降解细胞色素P - 450的反应机制。

Adv Exp Med Biol. 1981;136 Pt B:1213-20.

3

Reaction schemes for the degradation of cytochromes P-450 by allyl-isopropylacetamide and fluroxene.烯丙基异丙基乙酰胺和氟烯对细胞色素P - 450的降解反应机制。

Biochem Pharmacol. 1980 Oct 15;29(20):2805-14. doi: 10.1016/0006-2952(80)90015-5.

4

Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.2-烯丙基-2-异丙基乙酰胺对内源性和外源性血红素的破坏作用：苯巴比妥可诱导的肝脏细胞色素P-450的作用。

Int J Biochem. 1978;9(12):865-9. doi: 10.1016/0020-711x(78)90061-7.

5

Exogenous heme restores in vivo functional capacity of hepatic cytochrome P-450 destroyed by allylisopropylacetamide.外源性血红素可恢复被烯丙异丙基乙酰胺破坏的肝细胞色素P-450的体内功能。

Biochem Biophys Res Commun. 1979 Jul 27;89(2):456-63. doi: 10.1016/0006-291x(79)90651-x.

6

Allylisopropylacetamide preferentially interacts with the phenobarbital-inducible form of rat hepatic microsomal P-450.

Biochem Pharmacol. 1976 Nov 1;25(21):2415-7. doi: 10.1016/0006-2952(76)90042-3.

7

Breakdown of cytochrome P-450 heme by secobarbital and other allyl-containing barbiturates.司可巴比妥及其他含烯丙基巴比妥类药物对细胞色素P-450血红素的分解作用。

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8

Degradation of cytochrome P-450 haem by carbon tetrachloride and 2-allyl-2-isopropylacetamide in rat liver in vivo and in vitro. Involvement of non-carbon monoxide-forming mechanisms.四氯化碳和2-烯丙基-2-异丙基乙酰胺在大鼠肝脏体内外对细胞色素P-450血红素的降解作用。非一氧化碳生成机制的参与。

Biochem J. 1979 Dec 15;184(3):481-9. doi: 10.1042/bj1840481.

9

An investigation into the hepatic cytochrome P-450 catalysed metabolism of the anaesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether).关于麻醉药氟烯（2,2,2-三氟乙基乙烯基醚）的肝脏细胞色素P-450催化代谢的研究。

S Afr J Med Sci. 1975;40(4):205-17.

10

Fluroxene (2,2,2-trifluoroethyl vinyl ether) mediated destruction of cytochrome P-450 in vitro.氟罗克生（2,2,2-三氟乙基乙烯基醚）在体外介导的细胞色素P-450破坏作用。

Biochem Pharmacol. 1975 Nov 1;24(21):1933-6. doi: 10.1016/0006-2952(75)90377-9.

引用本文的文献

1

The effect of fluroxene [(2,2,2-trifluoroethoxy)ethane] on haem biosynthesis and degradation.氟烷（[2,2,2-三氟乙氧基]乙烷）对血红素生物合成及降解的影响。

Biochem J. 1980 Sep 15;190(3):571-80. doi: 10.1042/bj1900571.

2

Multiple forms of inducible drug-metabolizing enzymes: a reasonable mechanism by which any organism can cope with adversity.多种形式的诱导性药物代谢酶：一种任何生物体都能应对逆境的合理机制。

Mol Cell Biochem. 1979 Sep 28;27(1):27-46. doi: 10.1007/BF00849277.