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反射模式声光成象,采用一维超声阵及电子扫描聚焦。

Reflection-mode acousto-optic imaging using a one-dimensional ultrasound array with electronically scanned focus.

机构信息

University of Twente, Faculty of Science and Technology, Biomedical Photonic Imaging Group, Enschede, The Netherlands.

出版信息

J Biomed Opt. 2020 Sep;25(9). doi: 10.1117/1.JBO.25.9.096002.

Abstract

SIGNIFICANCE

Practical implementation of acousto-optic imaging (AOI) encounters difficulties that prevent it from rapid adoption in clinical use. In many practical medical applications, the region of interest may be accessed only from one side, and using a water tank for coupling is not feasible. The solution might be to use reflection-mode imaging with an electronically scanned ultrasound (US) focus. Such an approach, however, entails considerable challenges.

AIM

The possibilities of detecting and localizing light-absorbing inclusions inside turbid media by combining reflection-mode AOI conducted using a one-dimensional US array with electronic scanning of the US focus are investigated experimentally and signal processing algorithms that could be used for this purpose are introduced.

APPROACH

We determine the speckle contrast decrease due to the acousto-optic effect as a function of the US focal point coordinates. Different signal postprocessing techniques are investigated.

RESULTS

A significant decrease in the determined speckle contrast difference values is observed due to the presence of light-absorbing inclusions. However, local minima occur in the plots only under specific conditions. Subtracting individual distributions and determining symmetry deviations allow for localizing the inclusions.

CONCLUSIONS

Detection and localization of optically distinct regions are possible using the introduced approach. Signal postprocessing is required in a general case.

摘要

意义

声-光成象(AOI)的实际应用遇到了一些困难,这阻碍了它在临床应用中的快速采用。在许多实际的医学应用中,感兴趣的区域可能只能从一侧进入,而且使用水箱进行耦合是不可行的。解决办法可能是使用电子扫描超声(US)焦点的反射模式成像。然而,这种方法带来了相当大的挑战。

目的

通过结合使用一维 US 阵列进行的反射模式 AOI 和 US 焦点的电子扫描,研究检测和定位混浊介质中光吸收体的可能性,并介绍可用于此目的的信号处理算法。

方法

我们确定了由于声光效应导致的散斑对比度降低作为 US 焦点坐标的函数。研究了不同的信号后处理技术。

结果

由于存在光吸收体,观察到确定的散斑对比度差数值显著降低。然而,只有在特定条件下,图中才会出现局部最小值。通过减去单个分布并确定对称偏差,可以实现对包含物的定位。

结论

可以使用所介绍的方法进行光学上不同区域的检测和定位。在一般情况下需要进行信号后处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c276/7470216/cc297482db08/JBO-025-096002-g001.jpg

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