Lejay Anne, Vento Vincenzo, Kuntz Salomé, Steinmetz Lydie, Georg Yannick, Thaveau Fabien, Heim Frédéric, Chakfé Nabil
Department of Vascular Surgery and Kidney Transplantation, University Hospital of Strasbourg, Strasbourg, France -
Groupe Européen de Recherche sur les Prothèses Appliquées à la Chirurgie Vasculaire, Strasbourg, France -
J Cardiovasc Surg (Torino). 2020 Oct;61(5):538-543. doi: 10.23736/S0021-9509.20.11592-1. Epub 2020 Sep 4.
In the last decades, the main evolution in the field of vascular surgery was correlated to the development and introduction of vascular substitutes. Currently, two types of synthetic vascular substitutes have been widely adopted: polyethylene terephthalate and expanded polytetrafluoroethylene. Ideally, they should demonstrate a behavior as close as possible as that of human arteries in terms of mechanical and biological properties. However, no vascular substitute has been found to compare with the patency rates of gold-standard autologous conduits, and major drawbacks of current vascular substitutes remain both thrombogenicity and infectability.
在过去几十年中，血管外科领域的主要进展与血管替代物的开发和引入相关。目前，两种合成血管替代物已被广泛采用：聚对苯二甲酸乙二酯和膨体聚四氟乙烯。理想情况下，它们在机械和生物学特性方面应表现出尽可能接近人体动脉的性能。然而，尚未发现有血管替代物在通畅率方面能与金标准自体血管相媲美，并且当前血管替代物的主要缺点仍然是血栓形成倾向和易感染性。
