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股骨颈-头部区域的表观质量密度和杨氏模量的估算。

Estimation of mass apparent density and Young's modulus of femoral neck-head region.

机构信息

Department of Mechanical Engineering, Dr. Babasaheb Ambedkar Technological University, Lonere (Raigad), India.

出版信息

J Med Eng Technol. 2020;44(7):378-388. doi: 10.1080/03091902.2020.1799093. Epub 2020 Sep 4.

Abstract

The purpose of this study is to estimate mass apparent density and Young's modulus to investigate biomechanical properties of the proximal femur bone. In this study eleven specimens of sheep femur bone having age between 1-1.25 years and human femur bone having age between 14 and 81years are used. In the present study, the first technique attempts to estimate the density from the image-based Hounsfield unit which is obtained directly from a computed tomography image. The modulus of elasticity is estimated from density-elasticity relation which is available in the literature. Another technique is used to develop a correlation between computed apparent density and greyscale based coefficient obtained by material mapping method using commercial Simpleware ScanIP software. Estimated mean deviation in apparent mass density and Young's modulus is 4.34% and 4.69% in sheep bone and 4.35% and 4.94% in human bone respectively. It is found that apparent density and Young's modulus obtained shows close agreement with values reported in the literature. Moreover, the study attempts to build up a new material model between human and sheep for orthopaedics clinical trials and research in Indian context. In addition, it is also observed that bone mass density of sheep is 1.60 times human. This method can also be useful to study and analyse biomechanical properties of the human femur bone.

摘要

本研究旨在估算股骨近端骨的质量表观密度和杨氏模量,以研究其生物力学特性。本研究使用了 11 个绵羊股骨标本和 14 至 81 岁人类股骨标本。在本研究中,第一种技术试图从直接从计算机断层扫描图像获得的基于图像的亨氏单位估算密度。杨氏模量是根据文献中提供的密度-弹性关系估算的。另一种技术用于开发基于商用 Simpleware ScanIP 软件的材料映射方法获得的计算表观密度与灰度标度系数之间的相关性。在绵羊骨中,表观质量密度和杨氏模量的估计平均偏差分别为 4.34%和 4.69%,在人类骨中分别为 4.35%和 4.94%。结果表明,表观密度和杨氏模量与文献报道的值吻合较好。此外,本研究还试图在印度背景下为矫形临床试验和研究建立人类和绵羊之间的新材料模型。此外,还观察到绵羊的骨质量密度是人类的 1.60 倍。这种方法也可用于研究和分析人类股骨的生物力学特性。

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