Sohal Preet, Bregman Jana, Stokes Stacey, Whitehead Matthew T, Karwoski Bethany
George Washington University School of Medicine & Health Sciences, Washington, DC.
Department of Ophthalmology, Children's National Hospital, Washington, DC.
J AAPOS. 2020 Oct;24(5):316-319. doi: 10.1016/j.jaapos.2020.05.009. Epub 2020 Sep 2.
Tolosa-Hunt syndrome is a rare disorder characterized by granulomatous inflammation involving the cavernous sinus, superior orbital fissure, and/or orbit with no additional underlying cause. Tolosa-Hunt syndrome most often presents with painful ophthalmoplegia involving one or multiple cranial nerves. Here we report the case of an 8-year-old girl who presented, atypically, without the hallmark finding of pain. This case of pediatric Tolosa-Hunt syndrome is the only reported example to date lacking what is considered its pathognomonic feature and thus brings to light the clinical variability of this already inconspicuous disorder.
托洛萨-亨特综合征是一种罕见疾病,其特征为海绵窦、眶上裂和/或眼眶出现肉芽肿性炎症,且无其他潜在病因。托洛萨-亨特综合征最常表现为累及一条或多条颅神经的疼痛性眼肌麻痹。在此,我们报告一例8岁女孩的病例,该病例表现不典型,没有疼痛这一标志性表现。这例儿童托洛萨-亨特综合征是迄今为止唯一报道的缺乏其典型特征的病例,因此揭示了这种本就不常见疾病的临床变异性。