新型冠状病毒肺炎患者的淋巴细胞性心肌炎（4例尸检病例）

[Lymphocytic myocarditis in patients with COVID-19 (4 autopsy cases)].

作者信息

Kogan E A, Berezovsky Yu S, Kukleva A D, Kurilina E V, Semenova L A, Blagova O V, Zharkov N V

机构信息

Sechenov First Moscow State Medical University, Moscow, Russia.

Central Research Institute of Tuberculosis, Moscow, Russia.

出版信息

Arkh Patol. 2020;82(5):57-62. doi: 10.17116/patol20208205157.

DOI:10.17116/patol20208205157

PMID:33054033

Abstract

The paper describes 4 autopsy cases of myocarditis in elderly patients with confirmed coronavirus infection. It gives the data of a morphological study of heart specimens and a detailed characterization of a myocardial infiltrate. An immunohistochemical study with cellular infiltrate typing was performed. The fact that lymphocytic viral myocarditis can develop in COVID-19 was morphologically and immunohistochemically confirmed. The features of myocarditis in COVID-19 are the development of the former in the presence of coronaritis and the possibility of its concurrence with lymphocytic endo- and pericarditis.

摘要

本文描述了4例确诊感染冠状病毒的老年患者心肌炎尸检病例。文中给出了心脏标本的形态学研究数据以及心肌浸润的详细特征。进行了细胞浸润分型的免疫组织化学研究。从形态学和免疫组织化学方面证实了COVID-19可发生淋巴细胞性病毒性心肌炎。COVID-19心肌炎的特征是在存在冠状动脉炎的情况下发生前者，并且可能与淋巴细胞性心内膜炎和心包炎并发。