百日咳临床病例定义的敏感性和特异性。
Sensitivity and specificity of clinical case definitions for pertussis.
作者信息
Patriarca P A, Biellik R J, Sanden G, Burstyn D G, Mitchell P D, Silverman P R, Davis J P, Manclark C R
机构信息
Division of Immunization, Centers for Disease Control, Atlanta, GA 30333.
出版信息
Am J Public Health. 1988 Jul;78(7):833-6. doi: 10.2105/ajph.78.7.833.
Abstract
We evaluated the diagnostic performance of 15 clinical case definitions for pertussis in 233 patients who developed acute respiratory illness during community outbreaks in Wisconsin and Delaware. Using results from culture (Regan-Lowe media) and serology (Ig-class-specific ELISA) as diagnostic standards, cough for greater than or equal to 14 days was both sensitive (84 per cent-92 per cent) and specific (63 percent-90 per cent) in identifying patients with pertussis. This definition may be useful in monitoring pertussis outbreaks and for investigating contacts of culture-positive cases.
摘要
我们评估了15种百日咳临床病例定义在威斯康星州和特拉华州社区暴发期间出现急性呼吸道疾病的233例患者中的诊断性能。以培养（Regan-Lowe培养基）和血清学（Ig类特异性ELISA）结果作为诊断标准，咳嗽持续大于或等于14天在识别百日咳患者方面既敏感（84%-92%）又特异（63%-90%）。该定义可能有助于监测百日咳暴发以及调查培养阳性病例的接触者。
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