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Azithromycin for severe COVID-19.

作者信息

Oldenburg Catherine E, Doan Thuy

机构信息

Francis I Proctor Foundation, University of California, San Francisco, CA 94158, USA; Department of Ophthalmology, University of California, San Francisco, CA 94158, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158, USA.

Francis I Proctor Foundation, University of California, San Francisco, CA 94158, USA; Department of Ophthalmology, University of California, San Francisco, CA 94158, USA.

出版信息

Lancet. 2020 Oct 3;396(10256):936-937. doi: 10.1016/S0140-6736(20)31863-8. Epub 2020 Sep 5.

DOI:10.1016/S0140-6736(20)31863-8
PMID:32896293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7833672/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc63/7833672/485197351e9a/fx1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc63/7833672/485197351e9a/fx1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc63/7833672/485197351e9a/fx1_lrg.jpg

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Azithromycin for severe COVID-19.阿奇霉素用于治疗重症新型冠状病毒肺炎
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2
Azithromycin and SARS-CoV-2 infection: Where we are now and where we are going.阿奇霉素与 SARS-CoV-2 感染：我们现在在哪里，以及我们将走向何方。
J Glob Antimicrob Resist. 2020 Sep;22:680-684. doi: 10.1016/j.jgar.2020.06.016. Epub 2020 Jul 1.
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Hydroxychloroquine and azithromycin as a treatment of COVID-19.羟氯喹和阿奇霉素作为新型冠状病毒肺炎的一种治疗方法。
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Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.阿奇霉素联合标准治疗与标准治疗单独用于治疗巴西因重度 COVID-19 住院患者（COALITION II）：一项随机临床试验。
Lancet. 2020 Oct 3;396(10256):959-967. doi: 10.1016/S0140-6736(20)31862-6. Epub 2020 Sep 5.
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No evidence of clinical benefits of early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: Comment on "Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France".没有证据表明用羟氯喹和阿奇霉素对新冠病毒疾病患者进行早期治疗有临床益处：对《用羟氯喹和阿奇霉素对新冠病毒疾病患者进行早期治疗：法国马赛1061例回顾性分析》的评论
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Sci Rep. 2025 Jan 6;15(1):980. doi: 10.1038/s41598-024-79614-6.
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本文引用的文献

1
Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19.羟氯喹用于早期COVID-19非住院成人患者
Ann Intern Med. 2021 Mar;174(3):434-435. doi: 10.7326/L20-1426.
2
Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.阿奇霉素联合标准治疗与标准治疗单独用于治疗巴西因重度 COVID-19 住院患者（COALITION II）：一项随机临床试验。
Lancet. 2020 Oct 3;396(10256):959-967. doi: 10.1016/S0140-6736(20)31862-6. Epub 2020 Sep 5.
3
Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.
新型冠状病毒肺炎（COVID-19）：严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）变异株概述——当前疫苗和药物研发进展。
Biomed Res Int. 2023 Aug 29;2023:1879554. doi: 10.1155/2023/1879554. eCollection 2023.
4
Prediction of tsunami of resistance to some antibiotics is not far-fetched which used during COVID-19 pandemic.预测在新冠疫情期间使用的某些抗生素出现耐药性海啸并非牵强之事。
J Clin Lab Anal. 2023 Aug;37(15-16):e24959. doi: 10.1002/jcla.24959. Epub 2023 Aug 31.
5
Evolution of National Guidelines on Medicines Used to Treat COVID-19 in Pregnancy in 2020-2022: A Scoping Review.2020 - 2022年用于治疗妊娠期COVID - 19药物的国家指南演变：一项范围综述
J Clin Med. 2023 Jul 6;12(13):4519. doi: 10.3390/jcm12134519.
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Hydrogen Sulfide: Physiological Roles and Therapeutic Implications against COVID-19.硫化氢：对 COVID-19 的生理作用和治疗意义。
Curr Med Chem. 2024;31(21):3132-3148. doi: 10.2174/0929867330666230502111227.
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Towards the sustainable discovery and development of new antibiotics.迈向新型抗生素的可持续发现与开发。
Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19.
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Cytokine Profile of Invasive Pulmonary Aspergillosis in Severe COVID-19 and Possible Therapeutic Targets.重症新型冠状病毒肺炎侵袭性肺曲霉病的细胞因子谱及潜在治疗靶点
Diagnostics (Basel). 2022 Jun 1;12(6):1364. doi: 10.3390/diagnostics12061364.
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Res Social Adm Pharm. 2022 Oct;18(10):3855-3859. doi: 10.1016/j.sapharm.2022.05.008. Epub 2022 May 13.
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Acta Clin Croat. 2022 Feb;60(3):496-509. doi: 10.20471/acc.2021.60.03.21.
羟氯喹或联合阿奇霉素治疗轻中度 COVID-19。
N Engl J Med. 2020 Nov 19;383(21):2041-2052. doi: 10.1056/NEJMoa2019014. Epub 2020 Jul 23.
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Pharmaco-Immunomodulatory Therapy in COVID-19.COVID-19 的药物免疫调节治疗。
Drugs. 2020 Sep;80(13):1267-1292. doi: 10.1007/s40265-020-01367-z.
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A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.羟氯喹作为 COVID-19 暴露后预防的随机试验。
N Engl J Med. 2020 Aug 6;383(6):517-525. doi: 10.1056/NEJMoa2016638. Epub 2020 Jun 3.
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Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial.羟氯喹治疗主要为轻症和中症的 2019 冠状病毒病患者：开放标签、随机对照试验。
BMJ. 2020 May 14;369:m1849. doi: 10.1136/bmj.m1849.
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Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial.阿奇霉素对持续性未控制哮喘成人哮喘加重和生活质量的影响（AMAZES）：一项随机、双盲、安慰剂对照试验。
Lancet. 2017 Aug 12;390(10095):659-668. doi: 10.1016/S0140-6736(17)31281-3. Epub 2017 Jul 4.
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Zika virus cell tropism in the developing human brain and inhibition by azithromycin.寨卡病毒在发育中的人类大脑中的细胞嗜性及阿奇霉素对其的抑制作用
Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14408-14413. doi: 10.1073/pnas.1618029113. Epub 2016 Nov 29.
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Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells.阿奇霉素在囊性纤维化气道上皮细胞中的新型抗病毒特性。
Eur Respir J. 2015 Feb;45(2):428-39. doi: 10.1183/09031936.00102014. Epub 2014 Oct 30.
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Azithromycin induces anti-viral responses in bronchial epithelial cells.阿奇霉素诱导支气管上皮细胞抗病毒反应。
Eur Respir J. 2010 Sep;36(3):646-54. doi: 10.1183/09031936.00095809. Epub 2010 Feb 11.