HIV Prevention Research Unit, South African Medical Research Council, Cape Town, South Africa.
Aurum Institute, Johannesburg, South Africa.
AIDS Educ Prev. 2020 Aug;32(4):356-366. doi: 10.1521/aeap.2020.32.4.356.
Medical male circumcision is a proven method of HIV risk reduction in men with no known direct benefit to women. We investigated the benefit of partner circumcision on women's health. We conducted a secondary analysis of 5,029 women enrolled in the Vaginal and Oral Interventions to Control the Epidemic trial across 15 African sites, to look at the impact of partner circumcision status on sexually transmitted infections, pregnancy, frequency of sex, and condom use in women. Of 4,982 participants with a baseline response, 31% had circumcised partners. Women with circumcised partners had a significantly reduced risk of syphilis acquisition, hazard ratio 0.51 (0.26, 1.00), value = .05. Participants with uncircumcised partners were significantly less likely to have used a condom at the last sex act than the other two groups, adj. relative risk 0.86 (0.80, 0.92), adj. value < .0001. We found no evidence of sexual risk compensation in women with circumcised partners.
医学男性割礼是一种已被证实可降低男性感染 HIV 风险的方法，但对女性没有已知的直接益处。我们研究了伴侣割礼对女性健康的益处。我们对在非洲 15 个地点参加阴道和口腔干预控制艾滋病试验的 5029 名女性进行了二次分析，以研究伴侣割礼状况对女性的性传播感染、怀孕、性行为频率和避孕套使用的影响。在有基线反应的 4982 名参与者中，31%的女性伴侣接受了割礼。与其他两组相比，有割礼伴侣的女性感染梅毒的风险显著降低，风险比为 0.51（0.26，1.00），P 值为 0.05。与其他两组相比，有未割礼伴侣的参与者在最近一次性行为中使用避孕套的可能性显著降低，调整后的相对风险为 0.86（0.80，0.92），P 值<0.0001。我们没有发现有割礼伴侣的女性存在性风险补偿的证据。
