Department of Nanotechnology, Noorul Islam Centre for Higher Education, Kumaracoil, Thucklay, Kanyakumari, Tamilnadu 629180, India.
Department of Material Science and Nanotechnology, Yogivemana University, Kadapa 516005, India.
Int J Mol Sci. 2020 Sep 3;21(17):6440. doi: 10.3390/ijms21176440.
Scaffolds are important to tissue regeneration and engineering because they can sustain the continuous release of various cell types and provide a location where new bone-forming cells can attach and propagate. Scaffolds produced from diverse processes have been studied and analyzed in recent decades. They are structurally efficient for improving cell affinity and synthetic and mechanical strength. Carbon nanotubes are spongy nanoparticles with high strength and thermal inertness, and they have been used as filler particles in the manufacturing industry to increase the performance of scaffold particles. The regeneration of tissue and organs requires a significant level of spatial and temporal control over physiological processes, as well as experiments in actual environments. This has led to an upsurge in the use of nanoparticle-based tissue scaffolds with numerous cell types for contrast imaging and managing scaffold characteristics. In this review, we emphasize the usage of carbon nanotubes (CNTs) and CNT-polymer composites in tissue engineering and regenerative medicine and also summarize challenges and prospects for their potential applications in different areas.
支架对于组织再生和工程非常重要，因为它们可以持续释放各种细胞类型，并提供新的成骨细胞可以附着和繁殖的位置。近几十年来，已经研究和分析了来自各种工艺的支架。它们在结构上具有提高细胞亲和力和合成及机械强度的效率。碳纳米管是具有高强度和热惰性的海绵状纳米粒子，它们已被用作制造工业中的填充颗粒，以提高支架颗粒的性能。组织和器官的再生需要对生理过程进行显著的时空控制，以及在实际环境中的实验。这导致了基于纳米粒子的组织支架的大量使用，这些支架具有多种细胞类型，可用于对比成像和管理支架特性。在这篇综述中，我们强调了碳纳米管（CNT）和 CNT-聚合物复合材料在组织工程和再生医学中的应用，并总结了它们在不同领域的潜在应用所面临的挑战和前景。
