多壁碳纳米管-羟基磷灰石纳米复合材料涂层钛的生物相容性特征

Biocompatibility Characteristics of Titanium Coated with Multi Walled Carbon Nanotubes-Hydroxyapatite Nanocomposites.

作者信息

Park Jung-Eun, Jang Yong-Seok, Bae Tae-Sung, Lee Min-Ho

机构信息

Department of Dental Biomaterials and Institute of Biodegradable material, Institute of Oral Bioscience and BK21 plus project, School of Dentistry, Chonbuk National University, Jeonju 54896, Korea.

出版信息

Materials (Basel). 2019 Jan 10;12(2):224. doi: 10.3390/ma12020224.

Multi walled carbon nanotubes-hydroxyapatite (MWCNTs-HA) with various contents of MWCNTs was synthesized using the sol-gel method. MWCNTs-HA composites were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). HA particles were generated on the surface of MWCNT. Produced MWCNTs-HA nanocomposites were coated on pure titanium (PT). Characteristic of the titanium coated MWCNTs-HA was evaluated by field-emission scanning electron microscopy (FE-SEM) and XRD. The results show that the titanium surface was covered with MWCNTs-HA nanoparticles and MWCNTs help form the crystalized hydroxyapatite. Furthermore, the MWCNTs-HA coated titanium was investigated for in vitro cellular responses. Cell proliferation and differentiation were improved on the surface of MWCNT-HA coated titanium.

采用溶胶 - 凝胶法合成了具有不同多壁碳纳米管（MWCNTs）含量的多壁碳纳米管 - 羟基磷灰石（MWCNTs - HA）。通过X射线衍射（XRD）和透射电子显微镜（TEM）对MWCNTs - HA复合材料进行了表征。HA颗粒在MWCNT表面生成。将制备的MWCNTs - HA纳米复合材料涂覆在纯钛（PT）上。通过场发射扫描电子显微镜（FE - SEM）和XRD对涂覆有MWCNTs - HA的钛的特性进行了评估。结果表明，钛表面覆盖有MWCNTs - HA纳米颗粒，且MWCNTs有助于形成结晶的羟基磷灰石。此外，还研究了MWCNTs - HA涂覆的钛的体外细胞反应。在MWCNT - HA涂覆的钛表面，细胞增殖和分化得到了改善。