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术后膜状尿道长度是预测术后尿控恢复的唯一最重要的手术因素。

Postoperative membranous urethral length is the single most important surgical factor predicting recovery of postoperative urinary continence.

机构信息

Department of Urology, Bundang Jesaeng General Hospital, Seongnam, South Korea.

Department of Urology, Ajou University School of Medicine, Suwon, South Korea.

出版信息

Urol Oncol. 2020 Dec;38(12):930.e7-930.e12. doi: 10.1016/j.urolonc.2020.07.024. Epub 2020 Sep 6.

DOI:10.1016/j.urolonc.2020.07.024
PMID:32900623
Abstract

PURPOSE

To analyze the potential surgical factors affecting postoperative urinary continence, including postoperative membranous urethral length (MUL), in an era where open radical prostatectomy (ORP) and robot-assisted radical prostatectomy (RARP) coexist.

METHODS

Consecutive patients undergoing either ORP or RARP between April 2009 and June 2017 were included in this study. Pericatheter urethrography (PCU) was performed the day of catheter removal to confirm healing of the vesicourethral anastomosis and to measure PCU-MUL. Daily usage of incontinence pad was self-reported by the patient at each post-operative visit through a questionnaire. Univariate and multivariate analyses were performed to identify factors that influenced recovery of continence.

RESULTS

Of the 196 patients included, 121 and 75 patients received ORP and RARP, respectively. The cumulative full continence rates (0 pad/day) at 1 year in the ORP and RARP groups were 87% and 95%, respectively. In the univariate analysis, older age, high preoperative International Prostate Symptom Score (IPSS) irritative symptom domain, ORP, poorer NVB preservation, and shorter PCU-MUL were associated with delayed recovery of full continence. In the multivariate analysis, only older age, high preoperative IPSS irritative symptom domain, and shorter PCU-MUL remained as independent factors significantly associated with delayed recovery of full continence.

CONCLUSIONS

Our study highlights the importance of saving the MUL as long as possible in terms of continence recovery. This holds true for ORP even in the era of RARP and surgeons should not simply give up the prospect of early urinary continence in exchange for the patient's choice of ORP instead of RARP.

摘要

目的

分析影响术后尿控的潜在手术因素,包括术后膜部尿道长度(MUL),在开放根治性前列腺切除术(ORP)和机器人辅助根治性前列腺切除术(RARP)并存的时代。

方法

本研究纳入了 2009 年 4 月至 2017 年 6 月期间行 ORP 或 RARP 的连续患者。在拔除导尿管当天进行经导尿管尿道造影(PCU)以确认尿道膀胱吻合口愈合,并测量 PCU-MUL。患者在每次术后就诊时通过问卷自行报告失禁垫的每日使用情况。采用单因素和多因素分析来确定影响尿控恢复的因素。

结果

在纳入的 196 例患者中,121 例和 75 例分别接受了 ORP 和 RARP。ORP 和 RARP 组 1 年时的完全控尿累积率(0 垫/天)分别为 87%和 95%。在单因素分析中,年龄较大、术前国际前列腺症状评分(IPSS)刺激症状域较高、ORP、较好的神经血管束保护和较短的 PCU-MUL 与完全控尿恢复延迟相关。在多因素分析中,只有年龄较大、术前 IPSS 刺激症状域较高和较短的 PCU-MUL 仍然是与完全控尿恢复延迟相关的独立因素。

结论

我们的研究强调了在尿控恢复方面尽可能保存 MUL 的重要性。这对于 ORP 也是如此,即使在 RARP 时代,外科医生也不应该仅仅为了患者选择 ORP 而放弃早期尿控的前景,而不是选择 RARP。

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