不止有一个（Z 形锚）环！
Has More than a (Z Anchor) Ring to It!
机构信息
Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida, USA
出版信息
J Bacteriol. 2021 Jan 11;203(3). doi: 10.1128/JB.00460-20.
Abstract
The division and cell wall () cluster is a highly conserved region of the bacterial genome consisting of genes that encode several cell division and cell wall synthesis factors, including the central division protein FtsZ. The region immediately downstream of encodes the genes and is conserved across diverse lineages of Gram-positive bacteria and In some organisms, this region remains part of the cluster, but in others, it appears as an independent operon. A well-studied protein coded from this region is the positive FtsZ regulator SepF (YlmF), which anchors FtsZ to the membrane. Recent developments have shed light on the importance of SepF in a range of species. Additionally, new studies are highlighting the importance of the other conserved genes in this neighborhood. In this minireview, we aim to bring together the current research linking the region to cell division and highlight further questions surrounding these conserved genes.
摘要
该分隔和细胞壁（）簇是细菌基因组中高度保守的区域，包含编码几种细胞分裂和细胞壁合成因子的基因，包括中央分裂蛋白 FtsZ。位于 编码 基因的下游区域在革兰氏阳性菌和 的不同谱系中是保守的。在一些生物体中，该区域仍然是 簇的一部分，但在其他生物体中，它似乎是一个独立的操纵子。该区域编码的一种研究充分的蛋白质是正调控 FtsZ 的因子 SepF（YlmF），它将 FtsZ 锚定在膜上。最近的研究进展揭示了 SepF 在多种物种中的重要性。此外，新的研究强调了该邻近区域中其他保守基因的重要性。在这篇综述中，我们旨在汇集目前将 区域与细胞分裂联系起来的研究，并强调围绕这些保守基因的进一步问题。
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Has More than a (Z Anchor) Ring to It!不止有一个（Z 形锚）环！
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