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病例报告:登革热年轻归国旅行者的急性视力丧失。

Case Report: Acute Vision Loss in a Young Returning Traveler with Dengue Fever.

机构信息

1Division of Infectious Diseases, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

2Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

出版信息

Am J Trop Med Hyg. 2020 Nov;103(5):2026-2028. doi: 10.4269/ajtmh.20-0562.

DOI:10.4269/ajtmh.20-0562
PMID:32901600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7646753/
Abstract

Ocular complications are rare in patients with dengue fever, but may cause permanent loss of vision. We present the case of a 29-year-old German woman who developed severe acute vision loss because of dengue-associated maculopathy after traveling to Vietnam and Cambodia. Initially, the optical coherence tomography showed detachment of the retinal pigment epithelium, a central shift in the retinal pigmentation and intraretinal cysts. The patient was hospitalized and treated with a short course of intravenous prednisolone. Vision improved, and the patient showed full recovery at 9 months after the onset. This case highlights the importance of awareness and adequate management for ocular involvement in patients with dengue fever, including travelers.

摘要

眼部并发症在登革热患者中较为罕见,但可能导致永久性视力丧失。我们报告了一例 29 岁德国女性的病例,她在前往越南和柬埔寨旅行后因登革热相关性黄斑病变而出现严重的急性视力丧失。最初,光学相干断层扫描显示视网膜色素上皮脱离、视网膜色素中央移位和视网膜内囊肿。该患者住院并接受了短期静脉注射泼尼松龙治疗。视力有所改善,患者在发病后 9 个月时完全康复。本病例强调了对登革热患者(包括旅行者)眼部受累的认识和适当管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c68/7646753/354a2e4d0679/tpmd200562f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c68/7646753/f2dfb9000b80/tpmd200562f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c68/7646753/354a2e4d0679/tpmd200562f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c68/7646753/f2dfb9000b80/tpmd200562f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c68/7646753/354a2e4d0679/tpmd200562f2.jpg

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本文引用的文献

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Severe dengue in travellers: pathogenesis, risk and clinical management.旅行者中重症登革热:发病机制、风险和临床管理。
J Travel Med. 2019 Oct 14;26(7). doi: 10.1093/jtm/taz062.
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Ocular Manifestations of Emerging Flaviviruses and the Blood-Retinal Barrier.新兴黄病毒的眼部表现和血视网膜屏障。
Viruses. 2018 Sep 28;10(10):530. doi: 10.3390/v10100530.
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Dengue Maculopathy with Foveolitis in a Postpartum Female.一名产后女性的登革热黄斑病变伴小凹炎
Cureus. 2017 Dec 13;9(12):e1942. doi: 10.7759/cureus.1942.
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Epidemic arboviral diseases: priorities for research and public health.虫媒病毒性传染病:研究和公共卫生的优先事项。
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Ophthalmol Ther. 2012 Dec;1(1):2. doi: 10.1007/s40123-012-0002-z. Epub 2012 Aug 23.
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Optical coherence tomography patterns as predictors of visual outcome in dengue-related maculopathy.光学相干断层扫描模式可预测登革热相关性黄斑病变的视力结果。
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Foveolitis associated with dengue Fever: a case series.
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