古老的热休克基因是可有可无的。
Ancient heat shock gene is dispensable.
作者信息
Bardwell J C, Craig E A
机构信息
Department of Physiological Chemistry, University of Wisconsin Medical School, Madison 53706.
出版信息
J Bacteriol. 1988 Jul;170(7):2977-83. doi: 10.1128/jb.170.7.2977-2983.1988.
Abstract
Hsp83 is a major eucaryotic heat shock protein and one of the most conserved proteins known. We have isolated an Escherichia coli gene homologous to eucaryotic Hsp83 and used it to construct a deletion mutation. The E. coli mutant was viable but had a slight growth disadvantage that increased with temperature.
摘要
Hsp83是一种主要的真核热休克蛋白，也是已知最保守的蛋白之一。我们分离出了一个与真核Hsp83同源的大肠杆菌基因，并利用它构建了一个缺失突变体。该大肠杆菌突变体能够存活，但具有轻微的生长劣势，且这种劣势会随温度升高而加剧。
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