Alexandersson B T, Stefánsson T
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Reykjavik, Iceland.
Department of Surgery, The National University Hospital of Iceland, Reykjavik, Iceland.
BJS Open. 2020 Sep 9;4(6):1217-26. doi: 10.1002/bjs5.50336.
Diverticulitis is the most common complication of diverticular disease, affecting 10-25 per cent of patients with diverticula. A retrospective, nationwide, population-based cohort study was performed to analyse the incidence and recurrence rate of sigmoid diverticulitis requiring hospital admission.
All patients discharged from hospital in Iceland during 1985-2014 who were diagnosed with diverticular disease were included. The χ test was used to analyse the trend of the incidence in the period 2002-2014. The Kaplan-Meier method and the Cox model were used to analyse recurrence.
Of 8660 admissions for diverticular disease, 4746 were due to diverticulitis, of which 2939 were for diverticulitis diagnosed for the first time. After the first attack, surgery was used to treat 661 patients. Of 2278 patients not treated by resection, 537 had a second attack (23·6 per cent). There was a significant decrease in the incidence of diverticulitis in patients aged 40-89 years during the period from 2002 to 2014 (P = 0·033). The risk of recurrence was associated with younger age at first attack and female sex (P < 0·001).
There was a decline in the incidence of patients hospitalized with diverticulitis between 1995 and 2014, most prominent in older age groups. Different recurrence rates were reported in men and women, and in younger compared with older age groups.
憩室炎是憩室病最常见的并发症,影响10%至25%的憩室患者。开展了一项基于全国人群的回顾性队列研究,以分析需要住院治疗的乙状结肠憩室炎的发病率和复发率。
纳入1985年至2014年期间在冰岛出院的所有诊断为憩室病的患者。采用χ检验分析2002年至2014年期间发病率的趋势。采用Kaplan-Meier法和Cox模型分析复发情况。
在8660例因憩室病住院的患者中,4746例是由于憩室炎,其中2939例是首次诊断为憩室炎。首次发作后,661例患者接受了手术治疗。在2278例未接受切除术的患者中,537例再次发作(23.6%)。2002年至2014年期间,40至89岁患者的憩室炎发病率显著下降(P = 0.033)。复发风险与首次发作时年龄较小及女性性别相关(P < 0.001)。
1995年至2014年期间,憩室炎住院患者的发病率有所下降,在老年人群中最为明显。男性和女性以及较年轻与较年长年龄组的复发率有所不同。