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[母亲、胎儿与滋养层之间的特异性免疫关系。现代观点]

[Specific immune relationships among the mother, the fetus and the trophoblast. Present-day aspects].

作者信息

Vinatier D, Monnier J C

机构信息

Service de Gynécologie-Obstétrique, C.H.U. de Lille.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1988;17(2):166-72.

PMID:3290318
Abstract

Studying the literature, which is becoming larger and larger, the authors note that there is increasing understanding about the immune response that allows a harmonious development of the feto-placental unit. After the recognition of certain trophoblastic antigens there followed the activation of lymphocytes which synthesize substances favourable to trophoblastic growth. At the same time protective mechanisms which inhibit the generation and activation of immunological factors which are normally found when allografts are rejected, were recognized. Also recognized were other systems able to suppress aggressive features that can become active during pregnancy.

摘要

通过研究越来越多的文献,作者们注意到,对于允许胎儿 - 胎盘单位和谐发育的免疫反应的理解正在不断增加。在识别出某些滋养层抗原后,淋巴细胞被激活,这些淋巴细胞合成有利于滋养层生长的物质。同时,人们认识到存在保护机制,可抑制在同种异体移植被排斥时通常会出现的免疫因子的产生和激活。还认识到其他能够抑制在怀孕期间可能变得活跃的侵袭性特征的系统。

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