Vinatier D, Monnier J C, Dessaint J P
J Gynecol Obstet Biol Reprod (Paris). 1983;12(1):1-10.
The authors undertake a review of the literature so that they can point out present knowledge of the immunological relationship between mother and fetus. The fetus is a true allograft since it carries paternal antigens. Total harmony occurs so that immunisation of the mother against the feto-placental unit is recognised. This immunological reaction must occur to allow smooth development of the fetus with, at the same time, protection of the mother against trophoblastic invasion. Many regulatory mechanisms are summoned up to bring about this immunological response. While the progress in immunological knowledge has enabled us to glimpse this immunological relationship, it seems strongly probable that knowledge of these mechanisms can have applications outside gynaecology and obstetrics and be of equal value in the interpretation of immunological reactions which are found on oncology and parasitology.
作者对文献进行了综述，以便能够指出目前关于母婴免疫关系的知识。胎儿是一个真正的同种异体移植物，因为它携带父系抗原。实现了完全的协调，从而认识到母亲对胎儿 - 胎盘单位的免疫。这种免疫反应必须发生，以确保胎儿顺利发育，同时保护母亲免受滋养层细胞的侵袭。许多调节机制被调动起来以引发这种免疫反应。虽然免疫学知识的进步使我们能够瞥见这种免疫关系，但这些机制的知识很可能在妇科和产科之外有应用，并且在解释肿瘤学和寄生虫学中发现的免疫反应方面具有同等价值。
