Singal Archana, Kaur Ishmeet, Jakhar Deepak
Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, Delhi, India.
Department of Dermatology and STD, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, Delhi, India.
Skin Appendage Disord. 2020 Jul;6(4):247-249. doi: 10.1159/000508201. Epub 2020 Jun 9.
Fox-Fordyce disease (FFD) is a rare chronic skin disease of the apocrine unit. It presents chiefly in postpubertal females as grouped, monomorphic, skin-colored follicular papules associated with intense pruritus commonly in axillae but may involve pubic, perineal, areolar, and umbilical areas [. 2018;93(1):161-2]. Diagnosis is mostly clinical as histological features are often nonspecific and variable. However, the lesions at times may be mistaken for irritant contact dermatitis, lichen nitidus, syringoma, etc. [ 2009;36(9):485-90]. Dermoscopy is being increasingly utilized in pigmentary and inflammatory skin disorders. In this communication, we describe the dermoscopic features in FFD, which shows typical light brown to dark brown folliculocentric structureless areas with loss of dermatoglyphics. Some of the lesions also show hyperkeratotic follicular plugging.
福克斯-福代斯病（FFD）是一种罕见的顶泌汗腺单位慢性皮肤病。主要发生于青春期后的女性，表现为成群的、形态单一的肤色毛囊丘疹，常伴有剧烈瘙痒，常见于腋窝，但也可能累及耻骨、会阴、乳晕和脐部区域[2018；93(1):161 - 2]。诊断主要依靠临床，因为组织学特征往往不具有特异性且多变。然而，这些皮损有时可能被误诊为刺激性接触性皮炎、光泽苔藓、汗管瘤等[2009；36(9):485 - 90]。皮肤镜在色素性和炎症性皮肤病中的应用越来越广泛。在本报告中，我们描述了福克斯-福代斯病的皮肤镜特征，表现为典型的浅棕色至深棕色毛囊中心性无结构区域，皮纹消失。部分皮损还可见角化过度的毛囊堵塞。
