Hajian Pouran, Shabani Minoo, Khanlarzadeh Elham, Nikooseresht Mahshid
Department of Anesthesiology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
J Diabetes Res. 2020 Aug 21;2020:6725152. doi: 10.1155/2020/6725152. eCollection 2020.
Prolonged preoperative fasting is one of the concerns of pediatricians and anesthesiologists in pediatric surgery. The aim of this study was to assess the impact of preoperative fasting duration on blood glucose and hemodynamics in children.
This cross-sectional study was conducted on 50 children who were between the ages of 3 and 12 years in Besat Hospital, Hamedan, Iran. The time of the last solid and liquid meal taken by child were recorded based on interview with the parents. The first blood glucose test was obtained in the operation room, and the second test was performed 20 minutes after induction of anesthesia by glucometer. Systolic blood pressure (SBP), mean arterial pressure (MAP), and heart rate (HR) were recorded before anesthesia induction and in five-minute intervals in the first 20 minutes of surgery.
The mean age of the children was 6.63 (SD 1.85) years. Mean blood glucose 20 minutes after surgery was 101.17 (SD 92) mg/dl, which was significantly higher than the baseline values (87.66 (SD 11.84) mg/dl) ( < 0.001). The comparison of mean blood glucose level between groups of fasting with different duration for solids (<12 hours and >12 hours) and for liquids (<6 hours and >6 hours) revealed no significant difference in either groups ( > 0.05). No significant correlation was observed between blood glucose level at the induction of anesthesia with weight and age ( > 0.05). There was a significantly negative correlation between duration of fasting for liquids and SBP ( > 0.05).
Prolonged preoperative fasting cannot affect blood glucose in children; however, maybe it has impact on systolic blood pressure.
术前长时间禁食是小儿外科医生和麻醉医生关注的问题之一。本研究的目的是评估术前禁食时间对儿童血糖和血流动力学的影响。
本横断面研究在伊朗哈马丹贝萨特医院对50名3至12岁的儿童进行。通过与家长访谈记录儿童最后一次进食固体和液体食物的时间。在手术室进行首次血糖检测，并在麻醉诱导后20分钟用血糖仪进行第二次检测。在麻醉诱导前以及手术开始后的前20分钟每隔5分钟记录收缩压（SBP）、平均动脉压（MAP）和心率（HR）。
儿童的平均年龄为6.63（标准差1.85）岁。术后20分钟的平均血糖为101.17（标准差92）mg/dl，显著高于基线值（87.66（标准差11.84）mg/dl）（P<0.001）。对禁食不同时长的固体食物组（<12小时和>12小时）和液体食物组（<6小时和>6小时）的平均血糖水平进行比较，两组均无显著差异（P>0.05）。麻醉诱导时的血糖水平与体重和年龄之间未观察到显著相关性（P>0.05）。液体食物禁食时间与收缩压之间存在显著负相关（P>0.05）。
术前长时间禁食不会影响儿童血糖；然而，可能会对收缩压产生影响。
