Russo Alessandro, Coco Vito, Zaffagnini Stefano
II Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
J Surg Case Rep. 2020 Aug 31;2020(8):rjaa274. doi: 10.1093/jscr/rjaa274. eCollection 2020 Aug.
A prospective analysis of the effect of autologous adipose derived mesenchymal stem cell (AD-MSCs) therapy in the treatment of a juvenile osteochondritis dissecans (JOCD) of the patella. After failed conventional management of JOCD, a 13-year-old patient undergoes intra-articular MSC therapy. Repeated magnetic resonance imaging analyses showed regeneration of cartilage. In this report, the use of AD-MSCs, after unsuccessful conventional JOCD management, resulted in structural, functional and pain improvement. These results highlight the possibility to avoid surgery treatment in JOCD patella treatment.
自体脂肪间充质干细胞（AD-MSCs）治疗青少年髌骨剥脱性骨软骨炎（JOCD）效果的前瞻性分析。在JOCD的传统治疗失败后，一名13岁患者接受了关节内间充质干细胞治疗。反复的磁共振成像分析显示软骨再生。在本报告中，在传统JOCD治疗失败后使用AD-MSCs，导致结构、功能和疼痛改善。这些结果凸显了在JOCD髌骨治疗中避免手术治疗的可能性。
