Ravikanth Reddy
Department of Radiology, St. John's Hospital, Kattappana, Kerala, India.
J Craniovertebr Junction Spine. 2020 Apr-Jun;11(2):61-70. doi: 10.4103/jcvjs.JCVJS_56_20. Epub 2020 Jun 5.
Vertebral metastases represent an important cause of cancer-related morbidity and mortality. Among all available treatments, interventional percutaneous techniques have recently emerged as potential strategies for the management of oncologic patients with vertebral lesions. Minimally invasive image-guided therapies include "ablative" and "consolidative" ones. According to the number of metastases and the patient's performance status, ablative techniques can be performed with a curative or a palliative purpose since necrosis induced by critic changes of intralesional temperature determines both tumor debulking and destruction of pain receptors. On the other hand, consolidative treatments are based on the injection of polymethylmethacrylate cement to improve structural vertebral integrity and obtain pain alleviation and prevention of skeletal-related events. This article reviews the current recommendations supporting the role of interventional radiology in the management of vertebral metastases, focusing on the last updates in literature.
脊柱转移瘤是癌症相关发病和死亡的重要原因。在所有可用的治疗方法中，介入性经皮技术最近已成为治疗有脊柱病变的肿瘤患者的潜在策略。微创影像引导治疗包括“消融性”和“巩固性”治疗。根据转移灶数量和患者的体能状态，消融技术可用于根治性或姑息性治疗，因为病灶内温度的临界变化所诱导的坏死决定了肿瘤的减瘤和疼痛感受器的破坏。另一方面，巩固性治疗是基于注射聚甲基丙烯酸甲酯骨水泥来改善脊柱结构完整性，并缓解疼痛和预防骨相关事件。本文回顾了支持介入放射学在脊柱转移瘤治疗中作用的当前建议，重点关注文献中的最新进展。
