Department of Orthodontics, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Kalinga Nagar, Bhubaneswar 751003, Odisha, India.
Central Research Laboratory, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Kalinga Nagar, Bhubaneswar 751003, Odisha, India.
J Integr Med. 2020 Nov;18(6):462-469. doi: 10.1016/j.joim.2020.08.005. Epub 2020 Aug 19.
Probiotics are living bacterial cells that have significant therapeutic potential for treating human infectious diseases. There is a huge market for probiotics in the pharmaceutical sector. They have been frequently used to treat the gastrointestinal diseases and improve gut immunity. In this review, the strains currently in use for manufacturing oral probiotic formulations are discussed. The review further recommends the use of probiotics for the control of various oral health disorders, like dental caries, periodontitis, gingivitis, halitosis, burning mouth syndrome, and oral cancer. Finally, this review also explores the use of various commercial probiotic products in maintaining oral health, their market values, and government acts and regulations that are relevant to the production and marketing of probiotics. Probiotics have tremendous therapeutic potential and more in-depth research must be done on these beneficial bacteria to make them one of the leading drugs in treating oral disorders.
益生菌是具有重要治疗潜力的活菌细胞，可用于治疗人类传染病。在制药领域，益生菌有巨大的市场。它们经常被用于治疗胃肠道疾病和改善肠道免疫力。在这篇综述中，讨论了目前用于制造口服益生菌制剂的菌株。该综述进一步建议使用益生菌来控制各种口腔健康障碍，如龋齿、牙周炎、牙龈炎、口臭、口腔灼痛综合征和口腔癌。最后，本综述还探讨了各种商业益生菌产品在维护口腔健康方面的应用、它们的市场价值，以及与益生菌生产和销售相关的政府法案和法规。益生菌具有巨大的治疗潜力，必须对这些有益细菌进行更深入的研究，使它们成为治疗口腔疾病的主要药物之一。
