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针对肺癌退伍军人的战略举措。

Strategic Initiatives for Veterans with Lung Cancer.

作者信息

Moghanaki Drew, Hagan Michael

机构信息

is Section Chief of Radiation Oncology at the Atlanta VA Health Care System in Georgia. is Director of the Veterans Health Administration National Radiation Oncology Program in Richmond, Virginia.

出版信息

Fed Pract. 2020 Aug;37(Suppl 4):S76-S80. doi: 10.12788/fp.0019.

Abstract

BACKGROUND

Lung cancer is a leading cause of cancer-related mortality among veterans-as well as the US population-despite veterans' access to advanced medical technologies within the Veterans Health Administration (VHA). To improve outcomes, the VHA launched 3 lung cancer treatment initiatives in 2016 and 2017.

OBSERVATIONS

This article summarizes the VHA lung cancer initiatives and discusses future programs aimed to improve care for veterans. The US Department of Veterans Affairs (VA) Partnership to Increase Access to Lung Screening aims to reduce lung cancer mortality among veterans at risk by increasing access to low-dose computed tomography lung screening scans. The VALOR study is a randomized phase 3 clinical trial that evaluates optimal treatment for participants with operable early stage non-small cell lung cancer (NSCLC). This trial plans to enroll veterans with stage I NSCLC who will be randomly assigned to treatment with either surgical lobectomy or stereotactic body radiation therapy. Researchers will follow each participant for at least 5 years to evaluate which treatment, if either, results in a higher overall survival rate. The VA Radiation Oncology Quality Surveillance program compares treatment of veterans with lung cancer in the VHA with quality standards recommended by nationally recognized experts in lung cancer care.

CONCLUSIONS

The VHA continues to prioritize resources to improve and assure optimal outcomes for veterans with lung cancer. Future efforts include creating a national network of lung cancer centers of excellence to ensure that treatment decisions for veterans with lung cancer are based on all available molecular information, including data on pharmacogenomic profiles.

摘要

背景

尽管退伍军人可在退伍军人健康管理局(VHA)使用先进医疗技术,但肺癌仍是退伍军人以及美国人群中癌症相关死亡的主要原因。为改善治疗效果,VHA在2016年和2017年发起了3项肺癌治疗倡议。

观察结果

本文总结了VHA的肺癌倡议,并讨论了旨在改善退伍军人护理的未来计划。美国退伍军人事务部(VA)增加肺癌筛查可及性的伙伴关系旨在通过增加低剂量计算机断层扫描肺癌筛查扫描的可及性,降低有风险的退伍军人中的肺癌死亡率。VALOR研究是一项3期随机临床试验,评估可手术早期非小细胞肺癌(NSCLC)患者的最佳治疗方法。该试验计划招募I期NSCLC退伍军人,他们将被随机分配接受手术肺叶切除术或立体定向体部放射治疗。研究人员将对每位参与者进行至少5年的随访,以评估哪种治疗方法(如果有的话)能带来更高的总生存率。VA放射肿瘤学质量监测计划将VHA中退伍军人肺癌的治疗与肺癌护理领域全国公认专家推荐的质量标准进行比较。

结论

VHA继续将资源优先用于改善并确保肺癌退伍军人获得最佳治疗效果。未来的努力包括建立一个全国性的卓越肺癌中心网络,以确保肺癌退伍军人的治疗决策基于所有可用的分子信息,包括药物基因组学特征数据。

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本文引用的文献

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Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.随机试验中 CT 容积筛查降低肺癌死亡率
N Engl J Med. 2020 Feb 6;382(6):503-513. doi: 10.1056/NEJMoa1911793. Epub 2020 Jan 29.
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Int J Radiat Oncol Biol Phys. 2020 Mar 1;106(3):639-647. doi: 10.1016/j.ijrobp.2019.08.064. Epub 2020 Jan 23.
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