Department of Biomedical Engineering, Faculty of Mechanical Engineering, University of Zielona Gora, 9 Licealna Street, 65-417, Zielona Gora, Poland.
Department of Paediatric Urology, Cherry Clinic, Anieli Krzywon 2 Street, 65-534, Zielona Gora, Poland.
Urolithiasis. 2021 Feb;49(1):83-92. doi: 10.1007/s00240-020-01211-9. Epub 2020 Sep 9.
The aim of this work was to determine which part of a double-J ureteral stent (DJ stents) showed the highest tendency to crystal, calculi, and biofilm deposition after ureterorenoscopic-lithotripsy procedure (URS-L) to treat calcium oxalate stones. Additionally, the mechanical strength and the stiffness of DJ stents were evaluated before and after exposure to urine. Obtained results indicated that the proximal (renal pelvis) and distal (urinary bladder) part is the most susceptible for post-URS-L fragments and urea salt deposition. Both, the outer and inner surfaces of the DJ ureteral stents were completely covered even after 7 days of implantation. Encrustation of DJ stents during a 31-day period results in reducing the Young's modulus by 27-30%, which confirms the loss of DJ stent elasticity and increased probability of cracks or interruption. Performed analysis pointed to the need to use an antibacterial coating in the above-mentioned part of the ureteral stent to prolong its usage time and to prevent urinary tract infection.
本研究旨在确定经输尿管镜碎石术(URS-L)治疗草酸钙结石后,双 J 输尿管支架(DJ 支架)的哪个部位最容易出现结石、结晶和生物膜沉积。此外,还评估了 DJ 支架在暴露于尿液前后的机械强度和刚性。研究结果表明,DJ 支架的近端(肾盂)和远端(膀胱)部分最容易发生 URS-L 术后碎片和尿素盐沉积。DJ 输尿管支架的内外表面在植入后 7 天内完全被覆盖。DJ 支架在 31 天内的结壳会导致杨氏模量降低 27-30%,这证实了 DJ 支架弹性的丧失和出现裂缝或中断的可能性增加。分析表明,需要在输尿管支架的上述部位使用抗菌涂层,以延长其使用时间并预防尿路感染。