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当结局为非负且在零处聚集时,处理效应的半参数模型和推断。

Semiparametric models and inference for the effect of a treatment when the outcome is nonnegative with clumping at zero.

机构信息

University of California at San Francisco, San Francisco, California.

University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Biometrics. 2021 Dec;77(4):1187-1201. doi: 10.1111/biom.13368. Epub 2020 Sep 22.

Abstract

The outcome in a randomized experiment is sometimes nonnegative with a clump of observations at zero and continuously distributed positive values. One widely used model for a nonnegative outcome with a clump at zero is the Tobit model, which assumes that the treatment has a shift effect on the distribution of a normally distributed latent variable and the observed outcome is the maximum of the latent variable and zero. We develop a class of semiparametric models and inference procedures that extend the Tobit model in two useful directions. First, we consider more flexible models for the treatment effect than the shift effect of the Tobit model; for example, our models allow for the treatment to have a larger in magnitude effect for upper quantiles. Second, we make semiparametric inferences using empirical likelihood that allow the underlying latent variable to have any distribution, unlike the original Tobit model that assumes the latent variable is normally distributed. We apply our approach to data from the RAND Health Insurance Experiment. We also extend our approach to observational studies in which treatment assignment is strongly ignorable.

摘要

随机实验的结果有时是非负的,其中有一组观察值为零,并且连续分布着正数值。对于具有零簇的非负结果,一种广泛使用的模型是 Tobit 模型,它假设处理对正态分布潜在变量的分布有转移效应,并且观测结果是潜在变量和零的最大值。我们开发了一类半参数模型和推理程序,这些模型和程序在两个有用的方向上扩展了 Tobit 模型。首先,我们考虑比 Tobit 模型的转移效应更灵活的处理效应模型;例如,我们的模型允许处理对上分位数的影响更大。其次,我们使用允许潜在变量具有任何分布的经验似然进行半参数推断,与假设潜在变量正态分布的原始 Tobit 模型不同。我们将我们的方法应用于 RAND 健康保险实验的数据。我们还将我们的方法扩展到处理分配可以忽略不计的观察性研究中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02ec/8349173/8a95128b30b6/nihms-1717451-f0001.jpg

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