From the Department of Nuclear Medicine and Minnan PET Center.
Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.
Clin Nucl Med. 2020 Nov;45(11):913-915. doi: 10.1097/RLU.0000000000003263.
A 60-year-old woman, previously treated for breast cancer, was referred to gastroenterologists due to persistent abdominal distension. F-FDG PET/CT revealed multiple abnormal foci at the skeleton including the bilateral ilium, peritoneum, and omentum. Ga-FAPI PET/CT was performed for further detecting the primary lesion, which showed a greater number of bone metastases and higher uptake in peritoneal carcinomatoses than F-FDG. Biopsy at the left ilium and omentum indicated metastases from breast cancer. This case highlighted that Ga-FAPI may outperforms F-FDG PET/CT in identifying bone metastasis and peritoneal carcinomatosis.
一位 60 岁的女性，曾因乳腺癌接受治疗，因持续性腹胀被转介给胃肠病学家。F-FDG PET/CT 显示骨骼多处异常病灶，包括双侧髂骨、腹膜和大网膜。进行 Ga-FAPI PET/CT 以进一步检测原发性病变，结果显示骨转移病灶数量更多，腹膜癌病摄取量更高。左髂骨和大网膜活检表明乳腺癌转移。本病例提示 Ga-FAPI 可能优于 F-FDG PET/CT 用于识别骨转移和腹膜癌病。
