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经上皮光性角膜切削术治疗严重带状角膜病变。

Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy.

机构信息

Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Department of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Rd, Shanghai, 200092, People's Republic of China.

出版信息

Int Ophthalmol. 2020 Oct;40(10):2469-2474. doi: 10.1007/s10792-020-01574-3. Epub 2020 Sep 11.

Abstract

PURPOSE

The goal of this study was to investigate the clinical outcomes of transepithelial phototherapeutic keratectomy (transepithelial PTK) for the treatment of severe band keratopathy.

METHODS

A consecutive series of severe band keratopathy cases treated with transepithelial PTK were retrospectively analysed between January 2018 and December 2019. Severe band keratopathy was defined as corneal plaques apparent in the obscuration of iris details. Patients' medical histories, preoperative and postoperative symptomatic relief, cosmesis, best-corrected visual acuity (BCVA), complications, and recurrences were analysed.

RESULTS

Seventeen eyes of 16 patients were included in the study, with a mean follow-up of 9.8 ± 5.2 months (3 to 19 months). The mean age of the patients was 15.8 ± 10.2 years (8 to 46 years). Symptoms were significantly or completely relieved in all patients (100%). The results of cosmesis were good in 14 eyes (82.4%). Among those eyes that had BCVA of hand motion or better preoperatively, seven eyes (100%) showed an improvement in BCVA postoperatively. There were no complications or recurrences associated with transepithelial PTK treatment during the follow-up period.

CONCLUSIONS

Transepithelial PTK is an effective treatment to eliminate corneal opacity and alleviate symptoms in patients with severe band keratopathy. This technique could be an alternative approach to managing severe band keratopathy.

摘要

目的

本研究旨在探讨经上皮光性角膜切削术(transepithelial PTK)治疗严重带状角膜病变的临床效果。

方法

回顾性分析 2018 年 1 月至 2019 年 12 月期间采用经上皮 PTK 治疗的严重带状角膜病变患者的连续系列病例。严重带状角膜病变定义为角膜混浊导致虹膜细节无法辨认的斑块。分析患者的病史、术前和术后症状缓解、美容效果、最佳矫正视力(BCVA)、并发症和复发情况。

结果

本研究纳入了 16 例患者的 17 只眼,平均随访 9.8±5.2 个月(3 至 19 个月)。患者的平均年龄为 15.8±10.2 岁(8 至 46 岁)。所有患者的症状均明显或完全缓解(100%)。14 只眼(82.4%)的美容效果良好。在术前视力为手动或更好的眼中,术后 7 只眼(100%)BCVA 有所改善。在随访期间,经上皮 PTK 治疗未出现与并发症或复发相关的情况。

结论

经上皮 PTK 是一种有效治疗严重带状角膜病变的方法,可以消除角膜混浊并缓解症状。该技术可能是治疗严重带状角膜病变的一种替代方法。

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