Suppr超能文献

准分子激光光动力角膜切削术治疗硅油诱导的带状角膜病变。

Excimer laser phototherapeutic keratectomy for the treatment of silicone oil-induced band-shaped keratopathy.

机构信息

Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Eye Contact Lens. 2011 Sep;37(5):282-5. doi: 10.1097/ICL.0b013e31821269f1.

Abstract

PURPOSE

To study the efficacy of excimer laser phototherapeutic keratectomy (PTK) for the treatment of band-shaped keratopathy (BSK).

METHODS

A retrospective analysis of case records of 20 eyes of 20 patients with silicone oil-induced BSK and significant media haze that underwent PTK was conducted. Improvement in corneal clarity and best-corrected visual acuity (BCVA) was assessed at 6 weeks postoperatively.

RESULTS

The mean ablation depth was 62.63±23.82 μm (range 25 to 100 μm). Postoperative course was uneventful, and the mean time for healing of the epithelial defect was 4.25±2.43 days. All the eyes showed significant improvement in corneal clarity at 6 weeks postoperatively. The mean score of corneal clarity increased from 1.15±0.74 preoperatively to 3.35±0.49 at 6 weeks postoperatively (P<0.001). At postoperative 6 weeks, 90% (18 eyes) showed an improvement in BCVA of 2 or more lines, whereas the BCVA remained unchanged in two eyes (10%). There was a hyperopic shift postoperatively with a mean shift of spherical equivalent of 2.23±2.08 D. At the end of the last follow-up (mean: 16.75±4.2 months; range 11-24 months), two eyes with silicone oil in the vitreous chamber and with inferior peripheral and shallow retinal detachment showed recurrence of BSK for which retreatment with PTK was given.

CONCLUSIONS

Phototherapeutic keratectomy is an effective option for the treatment of silicone oil-induced BSK with significant improvement in corneal clarity. However, the gain in visual acuity depends on the coincident posterior segment pathologic condition. Further, in eyes with retained silicone oil, there is a risk of recurrence of BSK for which retreatment may be required.

摘要

目的

研究准分子激光光动力角膜切削术(PTK)治疗带状角膜病变(BSK)的疗效。

方法

回顾性分析了 20 例 20 眼硅油诱导的 BSK 伴明显介质混浊患者接受 PTK 的病例记录。术后 6 周评估角膜清晰度和最佳矫正视力(BCVA)的改善情况。

结果

平均消融深度为 62.63±23.82 μm(范围 25 至 100 μm)。术后过程顺利,上皮缺损愈合的平均时间为 4.25±2.43 天。所有患者术后 6 周角膜清晰度均显著改善。角膜清晰度平均评分从术前的 1.15±0.74 增加到术后 6 周的 3.35±0.49(P<0.001)。术后 6 周时,90%(18 眼)BCVA 提高 2 行或以上,而 2 眼(10%)BCVA 无变化。术后出现远视漂移,平均等效球镜漂移 2.23±2.08 D。末次随访结束时(平均:16.75±4.2 个月;范围 11-24 个月),2 眼硅油在玻璃体腔中,下方周边和浅层视网膜脱离,BSK 复发,再次接受 PTK 治疗。

结论

光动力角膜切削术是治疗硅油诱导的 BSK 的有效方法,可显著改善角膜清晰度。然而,视力的提高取决于并存的后节病理状况。此外,在硅油残留的眼中,BSK 有复发的风险,可能需要再次治疗。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验