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改良经上皮光疗性角膜切除术治疗带状角膜病变

Modified Transepithelial Phototherapeutic Keratectomy for Band Keratopathy.

作者信息

Shah Rachana Prashant, Nanavaty Mayank A

机构信息

Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BF, UK.

Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton BN2 5BF, UK.

出版信息

J Clin Med. 2024 Sep 25;13(19):5717. doi: 10.3390/jcm13195717.

Abstract

To report the outcomes of novel modified transepithelial phototherapeutic keratectomy (PTK) in treating band keratopathy (BK). A retrospective analysis was performed on patients who underwent PTK for BK at the Sussex Eye Laser Clinic, Nuffield Health, Brighton. Patients with BK obscuring the visual axis, affecting visual acuity, or causing discomfort were considered for PTK. All the patients underwent preoperative evaluation, including preoperative corneal topography and optical coherence tomography. Modified transepithelial PTK was performed without using EDTA for chelation or alcohol for epithelium debridement. Patients were followed up for one week and then every two weeks after that until two months. Preoperative and postoperative best corrected visual acuities (BCVA) were compared using a paired -test. We studied 15 eyes of nine patients undergoing novel PTK for BK. The mean age was 80 ± 5.73 years. The mean pre-treatment visual acuity was 0.68 ± 0.17 logMAR (range: 0.6 logMAR to 1 logMAR) and improved to 0.22 ± 0.09 logMAR ( < 0.05), ranging from 0.18 to 0.48 logMAR at two months following PTK. None of the patients complained of ocular discomfort following the procedure. A repeat procedure was not required for any of these patients. Modified transepithelial PTK is an effective procedure for improving visual outcomes in patients with band keratopathy and should be considered for the treatment of band keratopathy.

摘要

报告新型改良经上皮光疗性角膜切除术(PTK)治疗带状角膜病变(BK)的效果。对在布莱顿纳菲尔德健康中心苏塞克斯眼科激光诊所接受PTK治疗BK的患者进行回顾性分析。对于BK遮盖视轴、影响视力或引起不适的患者考虑行PTK。所有患者均接受术前评估,包括术前角膜地形图和光学相干断层扫描。改良经上皮PTK在不使用乙二胺四乙酸(EDTA)进行螯合或酒精进行上皮清创的情况下进行。患者随访1周,之后每2周随访1次,直至2个月。采用配对t检验比较术前和术后最佳矫正视力(BCVA)。我们研究了9例接受新型PTK治疗BK患者的15只眼。平均年龄为80±5.73岁。治疗前平均视力为0.68±0.17 logMAR(范围:0.6 logMAR至1 logMAR),PTK后2个月时提高至0.22±0.09 logMAR(P<0.05),范围为0.18至0.48 logMAR。术后无患者抱怨眼部不适。这些患者均无需再次手术。改良经上皮PTK是改善带状角膜病变患者视力的有效方法,应考虑用于带状角膜病变的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d210/11476468/368775b40a05/jcm-13-05717-g001.jpg

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