Department of Sense Organs, Eye Clinic, University "La Sapienza", Rome, Italy.
Eur J Ophthalmol. 2022 Jan;32(1):NP42-NP46. doi: 10.1177/1120672120969033. Epub 2020 Nov 5.
Calcific band keratopathy (CBK) is a relatively common chronic corneal degeneration and various forms of treatment are mentioned in the literature.
Two patients (89 and 37 yo, respectively) affected by diffuse long-standing CBK in one eye and complaining of ocular pain, foreign body sensation and decreased visual acuity are reported. An ethylenediaminetetraacetic acid (EDTA) application on the ocular surface was performed associated with a customized no-touch transepithelial phototherapeutic corneal remodeling in one patient and a standard phototherapeutic keratectomy (PTK) in the second patient. Corneal transparency progressively improved in both cases since the early follow-up visits and the cornea became clear 2 weeks after surgery. In both cases, a significant reduction of ocular discomfort was reported.
Combining EDTA chelation and excimer laser-assisted PTK represents an useful treatment of band keratopathy even in challenging cases and may help regularize corneal surface and improve corneal clarity.
钙化带角膜病变(CBK)是一种相对常见的慢性角膜变性,文献中提到了各种治疗方法。
报告了 2 名患者(分别为 89 岁和 37 岁),他们患有单侧弥漫性长期 CBK,伴有眼部疼痛、异物感和视力下降。对 1 名患者进行了表面的乙二胺四乙酸(EDTA)处理,并联合定制无接触式经上皮光疗角膜重塑术,对另 1 名患者进行了标准的光性角膜切削术(PTK)。在随访早期,2 例患者的角膜透明度均逐渐改善,术后 2 周角膜恢复透明。在这两种情况下,眼部不适均显著减轻。
EDTA 螯合与准分子激光辅助 PTK 联合治疗带角膜病变是一种有效的治疗方法,即使在具有挑战性的病例中也是如此,它可能有助于使角膜表面规则化,并提高角膜清晰度。