Harun Hanif Haspi, Abdul Karim Muhammad Khalis, Abbas Zulkifly, Abdul Rahman Mohd Amir, Sabarudin Akmal, Ng Kwan Hoong
Department of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Department of Radiology, Hospital Kuala Lumpur, Jalan Pahang, Kuala Lumpur 50586, Malaysia.
Diagnostics (Basel). 2020 Sep 9;10(9):681. doi: 10.3390/diagnostics10090681.
In this study, we aimed to estimate the probability of cancer risk induced by CT pulmonary angiography (CTPA) examinations concerning effective body diameter. One hundred patients who underwent CTPA examinations were recruited as subjects from a single institution in Kuala Lumpur. Subjects were categorized based on their effective diameter size, where 19-25, 25-28, and >28 cm categorized as Groups 1, 2, and 3, respectively. The mean value of the body diameter of the subjects was 26.82 ± 3.12 cm, with no significant differences found between male and female subjects. The risk of cancer in breast, lung, and liver organs was 0.009%, 0.007%, and 0.005% respectively. The volume-weighted CT dose index (CTDI) was underestimated, whereas the size-specific dose estimates (SSDEs) provided a more accurate description of the radiation dose and the risk of cancer. CTPA examinations are considered safe but it is essential to implement a protocol optimized following the As Low as Reasonably Achievable (ALARA) principle.
在本研究中，我们旨在评估计算机断层扫描肺动脉造影（CTPA）检查根据有效身体直径诱发癌症风险的概率。从吉隆坡的一家机构招募了100名接受CTPA检查的患者作为研究对象。根据有效直径大小对研究对象进行分类，其中19 - 25厘米、25 - 28厘米和>28厘米分别归为第1组、第2组和第3组。研究对象身体直径的平均值为26.82±3.12厘米，男性和女性研究对象之间未发现显著差异。乳腺、肺和肝脏器官的癌症风险分别为0.009%、0.007%和0.005%。体积加权CT剂量指数（CTDI）被低估，而特定尺寸剂量估计（SSDEs）能更准确地描述辐射剂量和癌症风险。CTPA检查被认为是安全的，但遵循合理可行尽量低（ALARA）原则实施优化方案至关重要。
