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身高增长速度与空腹胰岛素浓度之间的关系。

Relation between height velocity and fasting insulin concentrations.

作者信息

Hindmarsh P C, Matthews D R, Di Silvio L, Kurtz A B, Brook C G

机构信息

Endocrine Unit, Middlesex Hospital London.

出版信息

Arch Dis Child. 1988 Jun;63(6):665-6. doi: 10.1136/adc.63.6.665.

DOI:10.1136/adc.63.6.665
PMID:3291789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1778854/
Abstract

A linear relation between fasting serum insulin concentration and height velocity was found in 47 normal children. This suggests that doubling of growth velocity at puberty is accompanied by a two to threefold rise in insulin. This implies that insulin dosage should be increased by a similar magnitude in pubertal diabetic children during their growth spurt.

摘要

在47名正常儿童中发现空腹血清胰岛素浓度与身高增长速度之间存在线性关系。这表明青春期生长速度翻倍时,胰岛素会增加两到三倍。这意味着青春期糖尿病儿童在生长加速期胰岛素剂量应增加类似幅度。

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本文引用的文献

1
Both human pituitary growth hormone and recombinant DNA-derived human growth hormone cause insulin resistance at a postreceptor site.人垂体生长激素和重组DNA衍生的人生长激素都会在受体后位点引起胰岛素抵抗。
J Clin Endocrinol Metab. 1982 May;54(5):1033-8. doi: 10.1210/jcem-54-5-1033.